中医药导报
中醫藥導報
중의약도보
GUIDING JOURNAL OF TCM
2012年
12期
11-12
,共2页
林桂梅%张旭%尹丽波%侯影%杨静娴%贾天柱
林桂梅%張旭%尹麗波%侯影%楊靜嫻%賈天柱
림계매%장욱%윤려파%후영%양정한%가천주
枳实%胃动素%血管活性肠肽%胃泌素%生长抑素
枳實%胃動素%血管活性腸肽%胃泌素%生長抑素
지실%위동소%혈관활성장태%위비소%생장억소
Fructus aurantii immaturus%Motilin%Vasoactive intestinal peptide%Gastrin%Somatostatin
目的:研究枳实生品和麸炒品对利血平致脾虚证大鼠胃肠激素含量的影响.方法:腹腔注射利血平造成大鼠脾虚模型,双抗体夹心酶联免疫吸附法检测血中胃肠激素含量.结果:与模型组比较,枳实生品和麸炒品组大鼠胃动素和胃泌素水平升高,而血管活性肠肽和生长抑素水平降低,与模型组比较,差异均有统计学意义(P<0.05),并且麸炒品作用强于生品(P<0.05).结论:枳实生品和麸炒品均能改善利血平致脾虚证大鼠胃肠激素水平,这可能是枳实治疗脾虚证的机制之一.
目的:研究枳實生品和麩炒品對利血平緻脾虛證大鼠胃腸激素含量的影響.方法:腹腔註射利血平造成大鼠脾虛模型,雙抗體夾心酶聯免疫吸附法檢測血中胃腸激素含量.結果:與模型組比較,枳實生品和麩炒品組大鼠胃動素和胃泌素水平升高,而血管活性腸肽和生長抑素水平降低,與模型組比較,差異均有統計學意義(P<0.05),併且麩炒品作用彊于生品(P<0.05).結論:枳實生品和麩炒品均能改善利血平緻脾虛證大鼠胃腸激素水平,這可能是枳實治療脾虛證的機製之一.
목적:연구지실생품화부초품대리혈평치비허증대서위장격소함량적영향.방법:복강주사리혈평조성대서비허모형,쌍항체협심매련면역흡부법검측혈중위장격소함량.결과:여모형조비교,지실생품화부초품조대서위동소화위비소수평승고,이혈관활성장태화생장억소수평강저,여모형조비교,차이균유통계학의의(P<0.05),병차부초품작용강우생품(P<0.05).결론:지실생품화부초품균능개선리혈평치비허증대서위장격소수평,저가능시지실치료비허증적궤제지일.
Objective: To investigate the effect of raw and stir -frying with bran Fructus aurantii immaturus on gut hormone of spleen deficiency rats. Methods: The spleen deficiency rats model were established by injecting Reserpine. The gut hormone content was detected with ELISA. Results: Compared to the model group, the MTL, GAS content increased in raw Fructus aurantii immaturus group and stir-frying with bran Fructus aurantii immaturus group; the VIP and SS content declined in raw Fructus aurantii immaturus group and stir-frying with bran Fructus aurantii immaturus group. There was statistically significance between model group and sample group. Stir-frying with bran Fructus aurantii immaturus group was stronger than the raw Fructus aurantii immaturus group. Conclusion: Raw and stir-frying with bran Fructus aurantii immaturus could improve levels of guy hormones of the spleen deficiency rats, which might be one of the mechanisms for treating spleen deficiency of Fructus aurantii immaturus.