CAJ | 학술논문

目的:观察鲨螺硒胶囊(SLX)对免疫低下小鼠免疫功能的影响.方法:把免疫低下的小鼠进行分组对照试验.给药7 d后,观察、统计、分析各种对免疫功能有影响的因素.结果:小鼠灌胃鲨螺硒胶囊0.5 g/kg×7 d.(1)可对抗环磷酰胺(CTX)40 mg/kg×3 d引起的胸腺、脾脏指数下降,(2)显著地恢复CTX 15 mg/kg×3 d引起的血清溶血素降低,显著地恢复CTX 40 mg/kg×4 d引起的迟发型超敏反应低下;(3)鲨螺硒胶囊1 g/kg×7 d可提高CTX 25 mg/kg×6 d所致免疫低下小鼠脾淋巴细胞增殖率.结论:该制剂能增强免疫低下小鼠的免疫功能.
목적:관찰사라서효낭(SLX)대면역저하소서면역공능적영향.방법:파면역저하적소서진행분조대조시험.급약7 d후,관찰、통계、분석각충대면역공능유영향적인소.결과:소서관위사라서효낭0.5 g/kg×7 d.(1)가대항배린선알(CTX)40 mg/kg×3 d인기적흉선、비장지수하강,(2)현저지회복CTX 15 mg/kg×3 d인기적혈청용혈소강저,현저지회복CTX 40 mg/kg×4 d인기적지발형초민반응저하;(3)사라서효낭1 g/kg×7 d가제고CTX 25 mg/kg×6 d소치면역저하소서비림파세포증식솔.결론:해제제능증강면역저하소서적면역공능.
Objective: To observe the influence on immunosuppression of Shaluoxi Capsule in the mice, the immunity of which is low. Methods: The test was performed by grouping antitheses. And then observe, count and analyze the influence on immune function in 7 days. Results: (1) The thymus and spleen index decline, caused by the CTX with the concentration of 40 mg/kg for 3 days, can be against in mice with intragastric administration of Shaluoxi Capsule with the concentration of 0.5 g/kg;(2) The Serum hemolysin decline and low delayed-type hypersensitivity ,caused by CTX with the concentration of 15 mg/kg for 3 days, can be regained in in mice with intragastric administration of Shaluoxi Capsule with the concentration of 0.5 g/kg; (3) The spleen lymphocytes appreciation rate, caused by CTX with the concentration of 25 mg/kg for 6 days,can be improved in mice with intragastric administration of Shaluoxi Capsule with the concentration of 1 g/kg for 7 days.Conclusion:This prepara-tion can enhance immunity is low mice Immunosuppression caused by CTX.