CAJ | 학술논문

目的:探讨黄芪解毒汤对人乳腺癌裸鼠移植瘤的抑制效应.方法:采用人乳腺癌MCF-7细胞株建立乳腺癌模型,观察黄芪解毒汤高效剂量、等效剂量、低效剂量及参一胶囊、阿霉素对裸鼠一般情况、体重及移植瘤体积、重量的影响.结果:黄芪解毒汤对裸鼠生存质量无明显影响,与模型组比较,皮下移植瘤体积及重量差异有统计学意义(P<0.05).结论:黄芪解毒汤能抑制人乳腺癌裸鼠移植瘤的生长,且呈一定的剂量依赖关系,.
목적:탐토황기해독탕대인유선암라서이식류적억제효응.방법:채용인유선암MCF-7세포주건립유선암모형,관찰황기해독탕고효제량、등효제량、저효제량급삼일효낭、아매소대라서일반정황、체중급이식류체적、중량적영향.결과:황기해독탕대라서생존질량무명현영향,여모형조비교,피하이식류체적급중량차이유통계학의의(P<0.05).결론:황기해독탕능억제인유선암라서이식류적생장,차정일정적제량의뢰관계,.
Objective: To investigate the inhibitive effect of Astragalus Jie Du Decoction on breast carcinoma in nude mice. Methods: The model of Breast Carcinoma was established with MCF-7; the weight and subcutaneous transplant tumor a-mong different groups were compared. Results: There was no harm effect of Astragalus Jie Du Decoction on the nude mice, and that there was significant difference between the treated groups and the model group in terms of the weight and volume of the subcutaneous transplant tumor(P<0.05). Conclusion: Astragalus Ji Du Decoction can inhibit the grow of subcutaneous transplant tumor in nude mice,and there was a certain dose - dependent relationship. Objective: To investigate the inhibitive effect of Astragalus Jie Du Decoction on breast carcinoma in nude mice. Methods: The model of Breast Carcinoma was established with MCF-7; the weight and subcutaneous transplant tumor a-mong different groups were compared. Results: There was no harm effect of Astragalus Jie Du Decoction on the nude mice, and that there was significant difference between the treated groups and the model group in terms of the weight and volume of the subcutaneous transplant tumor(P<0.05). Conclusion: Astragalus Ji Du Decoction can inhibit the grow of subcutaneous transplant tumor in nude mice,and there was a certain dose - dependent relationship.