化学通报(网络版)
化學通報(網絡版)
화학통보(망락판)
Chemistry Online
2003年
1期
,共1页
邱文元%邓文叶%蔡艳桥%杨瑞青
邱文元%鄧文葉%蔡豔橋%楊瑞青
구문원%산문협%채염교%양서청
氨基酸%硒半胱氨酸%吡咯赖氨酸%密码子UAG%密码子UGA
氨基痠%硒半胱氨痠%吡咯賴氨痠%密碼子UAG%密碼子UGA
안기산%서반광안산%필각뢰안산%밀마자UAG%밀마자UGA
Amino acid%Selenocysteine%Pyrrolysine%UAG codon%UGA codon
介绍了已经发现的第21和22种天然氨基酸??硒半胱氨酸和吡咯赖氨酸.它们是由基因密码子直接编码的非标准氨基酸,其三联体密码子分别为UGA和UAG.这两种氨基酸与20种标准氨基酸编码方式不同,这引起了遗传密码子重新定义的变革.
介紹瞭已經髮現的第21和22種天然氨基痠??硒半胱氨痠和吡咯賴氨痠.它們是由基因密碼子直接編碼的非標準氨基痠,其三聯體密碼子分彆為UGA和UAG.這兩種氨基痠與20種標準氨基痠編碼方式不同,這引起瞭遺傳密碼子重新定義的變革.
개소료이경발현적제21화22충천연안기산??서반광안산화필각뢰안산.타문시유기인밀마자직접편마적비표준안기산,기삼련체밀마자분별위UGA화UAG.저량충안기산여20충표준안기산편마방식불동,저인기료유전밀마자중신정의적변혁.
This article introduces the undiscovered two amino acids? ? the 21st amino acid and the 22nd amino acid, which are called selenocysteine and pyrrolysine, respectively. They are nonstandard amino acids and directly encoded by genetic codes. Their RNA nucleotide triplets are UGA and UAG, respectively. The encoding way of these two amino acids, which are different from those twenty standard amino acids, lead to the problem of codon redefinition.