化学通报（网络版）
化學通報（網絡版）
화학통보（망락판）
Chemistry Online
2003年
1期
,共1页
刘福德%刘雁%李宝立%段艳馨%许国凤
劉福德%劉雁%李寶立%段豔馨%許國鳳
류복덕%류안%리보립%단염형%허국봉
5-二甲氨基甲基-2-呋喃甲醇%Mannich反应%雷尼替丁
5-二甲氨基甲基-2-呋喃甲醇%Mannich反應%雷尼替丁
5-이갑안기갑기-2-부남갑순%Mannich반응%뢰니체정
5-Dimethylaminomethyl-2-furanmethanol%Mannich reaction%Ranitidine
采用新工艺合成了5-二甲氨基甲基-2-呋喃甲醇,并利用IR及1H NMR对产品进行了结构表征.新工艺的特点是醋酸用量减少,反应时间缩短,产品收率高达82%,纯度为98.5%(气相色谱法).
採用新工藝閤成瞭5-二甲氨基甲基-2-呋喃甲醇,併利用IR及1H NMR對產品進行瞭結構錶徵.新工藝的特點是醋痠用量減少,反應時間縮短,產品收率高達82%,純度為98.5%(氣相色譜法).
채용신공예합성료5-이갑안기갑기-2-부남갑순,병이용IR급1H NMR대산품진행료결구표정.신공예적특점시작산용량감소,반응시간축단,산품수솔고체82%,순도위98.5%(기상색보법).
5-Dimethylaminomethyl-2-furanmethanol has been synthesized by new process and characterized by IR and 1H NMR.The advantage of the new process is that with less amount of HAc added and shorter time of reaction, the product yield is 82% which is higher than that of cited process(1) (2). The purity of the product is 98.5%(GC).
