CAJ | 학술논문

目的探讨苗药鸡胚地龙膏对急性腰痛的镇痛作用及其与患者预期的关系.方法采用随机双盲对照试验设计方法,选择138例急性腰痛患者,随机分为治疗组73例,采用鸡胚地龙膏治疗;对照组65例,采用跌打镇痛膏治疗,2组治疗疗程均为8 d.分别于治疗前、治疗2,4,6,8 d进行简式McGill疼痛问卷(SF-MPQ)、重复改良的Schober试验(MMS)、预期和治疗信任度问卷(ETCS)评分及观察不良反应情况.结果治疗4,6,8 d后,治疗组感觉项总分(S-PRI)、情感项总分(A-PRI)、疼痛评分指数总分(T-PRI)、视觉模拟评分(VAS)、现实疼痛强度评分(PPI)及MMS评分与对照组比较,差异均有统计学意义(P<0.01);治疗8 d,治疗组ETCS1、ETCS2、ETCS3、ETCS4及ETCS合计值分别与对照组比较,差异均有统计学意义(P<0.01).2组治疗期间均未见不良反应发生.结论鸡胚地龙膏能显著减轻急性腰痛患者的疼痛,起效迅速,安全、无毒副作用,是一种治疗急性腰痛较为理想的药物.
목적탐토묘약계배지룡고대급성요통적진통작용급기여환자예기적관계.방법채용수궤쌍맹대조시험설계방법,선택138례급성요통환자,수궤분위치료조73례,채용계배지룡고치료;대조조65례,채용질타진통고치료,2조치료료정균위8 d.분별우치료전、치료2,4,6,8 d진행간식McGill동통문권(SF-MPQ)、중복개량적Schober시험(MMS)、예기화치료신임도문권(ETCS)평분급관찰불량반응정황.결과치료4,6,8 d후,치료조감각항총분(S-PRI)、정감항총분(A-PRI)、동통평분지수총분(T-PRI)、시각모의평분(VAS)、현실동통강도평분(PPI)급MMS평분여대조조비교,차이균유통계학의의(P<0.01);치료8 d,치료조ETCS1、ETCS2、ETCS3、ETCS4급ETCS합계치분별여대조조비교,차이균유통계학의의(P<0.01).2조치료기간균미견불량반응발생.결론계배지룡고능현저감경급성요통환자적동통,기효신속,안전、무독부작용,시일충치료급성요통교위이상적약물.
Objective To assess the analgesic effect of Jipei ointment on acute lumbago and the relationship between the analgesic effect and the expectation of patients.Methods A randomized, double blind,controlled trial was designed.138 cases of acute lumbago were randomly divided into two groups,73 cases were in the treatment group and 65 cases were in the control group. The course in two groups was 8 days. simplified McGill pain questionnaire(SF-MPQ), Schober test and repeated modified (MMS)treatment, expectations and trust questionnaire (ETCS)score and adverse reactions were observed before treatment, 2, 4, 6, 8 days Respectively. Results 4, 6, 8 days after treatment group, sensory score(S-PRI), emotional score(A-PRI), pain rating index score(T-PRI), visual analogue scale(VAS), the reality of pain intensity score (PPI) score and MMS score were compared with control, the differences were statistically significant(P<0.01);8 D treatment, treatment group ETCS1, ETCS2, ETCS3, ETCS4 and ETCS total value respectively, compared with the control group, the difference was statistically significant (P<0.01). During the treatment there was no adverse reaction in the 2 groups. Conclusion Jipei ointment can reduce acute pain of lumbago significantly. It is rapid, safe, non-toxic side effects, it was an ideal drug to treat acute lumbago.