基层医学论坛
基層醫學論罈
기층의학론단
PUBLIC MEDICAL FORUM MAGAZINE
2013年
4期
414-415
,共2页
N-末端脑钠肽前体%高血压%左室舒张末期内径%相关性
N-末耑腦鈉肽前體%高血壓%左室舒張末期內徑%相關性
N-말단뇌납태전체%고혈압%좌실서장말기내경%상관성
N- terminal pro-brain natriuretic peptide% (NT-proBNP)%Hypertension%Left ventricular end diastolic diameter(LVEDd)%Correlation
目的探究N-末端脑钠肽前体(NT-proBNP)检测在高血压患者中的意义.方法306例高血压确诊患者按标准进行分级分组,208例同期体检无高血压者为对照组,共同检测血浆NT-proBNP以及行心脏超声检查.结果2级、3级高血压患者血浆NT-proBNP水平及左心室舒张末期内径(LVEDd)明显高于对照组,左心室射血分数(LVEF)明显低于对照组(P<0.01);1级高血压患者血浆NT-proBNP水平、LVEDd、LVEF与对照组比较差异无统计学意义(P>0.05).结论在高血压患者中,血浆NT-BNP水平与高血压分级以及左室构型之间有较好的相关性,为诊断早期高血压心脏病一种快捷、简便的方法.
目的探究N-末耑腦鈉肽前體(NT-proBNP)檢測在高血壓患者中的意義.方法306例高血壓確診患者按標準進行分級分組,208例同期體檢無高血壓者為對照組,共同檢測血漿NT-proBNP以及行心髒超聲檢查.結果2級、3級高血壓患者血漿NT-proBNP水平及左心室舒張末期內徑(LVEDd)明顯高于對照組,左心室射血分數(LVEF)明顯低于對照組(P<0.01);1級高血壓患者血漿NT-proBNP水平、LVEDd、LVEF與對照組比較差異無統計學意義(P>0.05).結論在高血壓患者中,血漿NT-BNP水平與高血壓分級以及左室構型之間有較好的相關性,為診斷早期高血壓心髒病一種快捷、簡便的方法.
목적탐구N-말단뇌납태전체(NT-proBNP)검측재고혈압환자중적의의.방법306례고혈압학진환자안표준진행분급분조,208례동기체검무고혈압자위대조조,공동검측혈장NT-proBNP이급행심장초성검사.결과2급、3급고혈압환자혈장NT-proBNP수평급좌심실서장말기내경(LVEDd)명현고우대조조,좌심실사혈분수(LVEF)명현저우대조조(P<0.01);1급고혈압환자혈장NT-proBNP수평、LVEDd、LVEF여대조조비교차이무통계학의의(P>0.05).결론재고혈압환자중,혈장NT-BNP수평여고혈압분급이급좌실구형지간유교호적상관성,위진단조기고혈압심장병일충쾌첩、간편적방법.
Objective The detection significance of N-terminal brain natriuretic peptide precursor was discussed in patients of hypertension.Methods 306 cases of hypertensive patients were grouped according to the standard of classification, 208 cases without hypertension were in control group, they received the detection of plasma NT-proBNP and cardiac ultrasound examination.Results The plasma levels of NT-proBNP and left ventricular end diastolic diameter(LVEDd)in patients with grade 2, grade 3 hypertension, was significantly higher than that of the control group, the left ventricular ejection fraction (LVEF)was significantly lower than that in the control group (P<0.01);there were no significant difference about plasma levels of NT-proBNP, LVEDd, LVEF in grade 1 hypertension patients compared with those in the control group (P>0.05). Conclusion In hypertensive patients, there is a good correlation between plasma NT-BNP level and the grade of hypertension and left ventricular geometry, which is a fast, simple method for diagnosis of early hypertensive heart disease.
