CAJ | 학술논문

目的观察盐酸右美托咪定用于临床麻醉中的效果,确定有效、安全的麻醉方案.方法将120例进行全身麻醉的肺叶切除手术患者随机分为A组和B组.A组选用生理盐水、咪达唑仑、维库溴铵、舒芬太尼、丙泊酚;B组选用盐酸右美托咪定、咪达唑仑、维库溴铵、舒芬太尼、丙泊酚.分别记录麻醉药物用量、时间指标及各时间点患者的血流动力学情况.结果右美托咪定有利于插管和拔管的平稳;患者丙泊酚的用量B组小于A组,差异有统计学意义;B组相对于A组具有较短的苏醒时间、拔管时间、自主呼吸恢复时间,差异不具有统计学意义.结论麻醉过程中加用盐酸右美托咪定,可明显削弱麻醉插管的应激反应,降低丙泊酚的用量,保持血流动力学的稳定性,显著提高患者满意度.
목적관찰염산우미탁미정용우림상마취중적효과,학정유효、안전적마취방안.방법장120례진행전신마취적폐협절제수술환자수궤분위A조화B조.A조선용생리염수、미체서륜、유고추안、서분태니、병박분;B조선용염산우미탁미정、미체서륜、유고추안、서분태니、병박분.분별기록마취약물용량、시간지표급각시간점환자적혈류동역학정황.결과우미탁미정유리우삽관화발관적평은;환자병박분적용량B조소우A조,차이유통계학의의;B조상대우A조구유교단적소성시간、발관시간、자주호흡회복시간,차이불구유통계학의의.결론마취과정중가용염산우미탁미정,가명현삭약마취삽관적응격반응,강저병박분적용량,보지혈류동역학적은정성,현저제고환자만의도.
Objective To observe and compare the effectiveness analysis on addition of dexmedetomidine hydrochloride to general anesthesia program,which given a reference for choosing an effective and safe anesthesia program. Methods 120 cases of pulmonary lobectomy operation under general anesthesia were randomly divided into A group and B group. A group used saline, midazolam, propofol, sufentanil, vecuronium bromide; B group used dexmedetomidine hydrochloride, midazolam, propofol, sufentanil, vecuronium bromide. The hemodynamic situation of anesthetic drug dosage, time and each time point of patient were recorded.Results Dexmedetomidine hydrochloride insure the stability of intubation tube and tube drawing,the dosage of propofol for group B is less than that of group A, and similar as the revival,extubation and spontaneous recovery time.Conclusion From the perspective of patients,the anesthesia program addition to dexmedetomidine hydrochloride could significantly reduce the need handling adverse reaction rates and the amount of propofol,it also could reduce the stress response during intubation,improve patient satisfaction after surgery and maintain hemodynamic stability.