CAJ | 학술논문

目的探讨经静脉心肌超声造影过程中触发间隔长短对急性心肌梗死后“危险区”面积测定的影响.方法采用冠状动脉左前降支结扎法建立兔急性心肌梗死模型,经静脉持续匀速输注自制高分子材料超声造影剂(高聚显),应用间断谐波成像,在不同的触发间隔下,判定心肌超声造影触发间隔长短对急性心肌梗死后“危险区”面积测量的影响,及定量触发间隔对“危险区”面积测量的影响程度.结果在触发间隔为1~10 RR 时,测定的“危险区”面积随触发间隔的延长而减小,但10 RR 后“危险区”面积不再减小.心肌微血管内的造影剂进出已经达到平衡,即10 RR 后的“危险区”就是真正的无血流灌注区.结论触发间隔长短对左室乳头肌短轴切面“危险区”面积的测量有明显影响,在持续静脉输注法行超声造影动态评价心肌“危险区”面积时一定要充分考虑到触发间隔这一影响参数.
목적탐토경정맥심기초성조영과정중촉발간격장단대급성심기경사후“위험구”면적측정적영향.방법채용관상동맥좌전강지결찰법건립토급성심기경사모형,경정맥지속균속수주자제고분자재료초성조영제(고취현),응용간단해파성상,재불동적촉발간격하,판정심기초성조영촉발간격장단대급성심기경사후“위험구”면적측량적영향,급정량촉발간격대“위험구”면적측량적영향정도.결과재촉발간격위1~10 RR 시,측정적“위험구”면적수촉발간격적연장이감소,단10 RR 후“위험구”면적불재감소.심기미혈관내적조영제진출이경체도평형,즉10 RR 후적“위험구”취시진정적무혈류관주구.결론촉발간격장단대좌실유두기단축절면“위험구”면적적측량유명현영향,재지속정맥수주법행초성조영동태평개심기“위험구”면적시일정요충분고필도촉발간격저일영향삼수.
Objective To investigate the influence of different trigger interval on measuring risk areas of acute myocardial infarction during myocardial contrast echocardiography (MCE). Methods The model of rabbits with acute myocardial infarction were conducted. MCE was performed using intermittent harmonic imaging with 15 trigger intervals through the intravenous injection of self -made contrast agent. The imagings were stored and analyzed as follows: (a) to investigate the influence of different trigger interval on measuring risk areas of acute myocardial infarction at mid papillary muscle level in the short-axis view.(b) to quantitative the effect of trigger interval on the measurement of risk areas. Results With the increase of trigger interval, the risk area measured at 1~10 RR trigger interval reduced. But the risk area measured at more than 10 RR trigger interval was no longer reduced, indicating the risk area measured at more than 10 RR trigger interval was “real” no flow perfusion. Conclusion There was significant effect of trigger interval on measurement risk area of the short-axis plane at mid papillary muscle level, and the parameter of trigger interval must be considered when continuous intravenous injection of contrast agent for MCE to evaluate risk area.