CAJ | 학술논문

目的:探索社区医院对妊娠期梅毒患者防护优势.方法:对56例经血清学检查确诊为妊娠合并梅毒患者,其中45例通过苄星青霉素治疗,按治疗孕期分为四组,孕期0~12周治疗组(A组22例);B:孕中期13~28周治疗组(B组14例),孕晚期29~40周治疗组(C组9例)和未治疗组(D组11例).比较孕妇的妊娠结局及新生儿预后情况.结果:治疗组在足月产、胎膜早破、畸胎和死胎流产方面与未治疗组比较差异有统计学意义(P<0.05或P<0.01),四组患者新生儿情况比较治疗组分娩正常新生儿成功率81.8%,围产儿死亡率仅为4.5%,先天梅毒为18.2%;非治疗组分娩正常新生儿率27.3%,围产儿死亡率54.5%,先天梅毒72.7%,两组比较X2=19.33,P<0.001,孕早期、孕中期治疗组较孕晚期治疗组和非治疗组围产儿预后良好.结论:充分利用社区医院对传染病防控及诊治方便的优势,加强妊娠梅毒筛查管理及孕期抗梅毒治疗,有效地降低妊娠梅毒的不良妊娠结局.
목적:탐색사구의원대임신기매독환자방호우세.방법:대56례경혈청학검사학진위임신합병매독환자,기중45례통과변성청매소치료,안치료잉기분위사조,잉기0~12주치료조(A조22례);B:잉중기13~28주치료조(B조14례),잉만기29~40주치료조(C조9례)화미치료조(D조11례).비교잉부적임신결국급신생인예후정황.결과:치료조재족월산、태막조파、기태화사태유산방면여미치료조비교차이유통계학의의(P<0.05혹P<0.01),사조환자신생인정황비교치료조분면정상신생인성공솔81.8%,위산인사망솔부위4.5%,선천매독위18.2%;비치료조분면정상신생인솔27.3%,위산인사망솔54.5%,선천매독72.7%,량조비교X2=19.33,P<0.001,잉조기、잉중기치료조교잉만기치료조화비치료조위산인예후량호.결론:충분이용사구의원대전염병방공급진치방편적우세,가강임신매독사사관리급잉기항매독치료,유효지강저임신매독적불량임신결국.
Objective:To explore the community hospitals of patients with syphilis during pregnancy protection advantages .Meth-ods:56 cases of Syphilis serology diagnosed as gestational patients ,including 45 cases of which were treated with benzathine penicillin therapy,the treatment based on the duratien of pregnancy is divided into four groups , pregnancy 0~12w treatment group (A group n=22 ) ;B:second trimester 13~28w treatment group (B group , n =14 ) , and third trimester of pregnancy 29~40w treatment group (C group , n =9) and untreated (D group n=11).Results:The treatment group in term labor , premature rupture of mem-branes , birth defects and stillbirths abortion compared with no treatment group difference was statistically significant (P<0.05 or P<0.01).Four groups of patients with neonatal treatment group has got the normal newborn successful rate of 81.8%, the perinatal mor-tality rate was only 4.5%congenital syphilis to 18.2%;non -treatment group childbirth normal newborn rate of 27.3%, Perinatal mortality rate of 54.5%, and 72.7%of congenital syphilis , the two groups compare X 2 =19.33 , P<0.001,first trimester , second trimester treatment group compared with the third trimester treatment group and the non -treatment group perinatal prognosis is good . Conclusion:The full use of community hospitals convenience advantages of infectious disease prevention , diagnosis and treatment , strengthen syphilis screening in pregnancy management and anti -syphilis treatment during pregnancy ,effectively reduces the adverse pregnancy outcomes of pregnancy syphilis .