CAJ | 학술논문

目的:了解近年来上海样本医院抗感染用药变化趋势,供科研、生产、销售和使用部门参考.方法:采用2009-2011年上海119家样本医院抗感染用药数据,统计大类和品种的金额、份额、增长率、复合年均增长率等,结合临床应用的情况进行分析和讨论.结果:近年来政府采取一系列深化医疗改革的措施,并对不合理应用抗菌药物,开展专项整治活动.上海样本医院用药持续增长,但增幅趋缓,抗感染用药上升势头得到明显遏制,增长率远低于全部用药,其中2011年第一次出现负增长.用药品种虽有差异,但总体第四、第三代头孢菌素和喹诺酮类等使用比例下降,青霉素类、第一代头孢菌素等使用比例上升,呈现良好的发展态势,抗菌药物整治初显成效.结论:抗感染药是最常用的药物之一,应继续加强药政管理,合理应用,减缓细菌耐药性的产生和发展.
목적:료해근년래상해양본의원항감염용약변화추세,공과연、생산、소수화사용부문삼고.방법:채용2009-2011년상해119가양본의원항감염용약수거,통계대류화품충적금액、빈액、증장솔、복합년균증장솔등,결합림상응용적정황진행분석화토론.결과:근년래정부채취일계렬심화의료개혁적조시,병대불합리응용항균약물,개전전항정치활동.상해양본의원용약지속증장,단증폭추완,항감염용약상승세두득도명현알제,증장솔원저우전부용약,기중2011년제일차출현부증장.용약품충수유차이,단총체제사、제삼대두포균소화규낙동류등사용비례하강,청매소류、제일대두포균소등사용비례상승,정현량호적발전태세,항균약물정치초현성효.결론:항감염약시최상용적약물지일,응계속가강약정관리,합리응용,감완세균내약성적산생화발전.
ABSTRACT Objective: To understand the medication trends of anti-infective agents trends in Shanghai sample hospitals in recent years so as to provide a reference for scientific research, production and marketing. Methods:Data for anti-infective agents in 119 sample hospitals of Shanghai during 2009-2011 were used to count the sales, shares, growth rates and compound annual growth rate of statistical categories and varieties, which were analyzed by combineation with their application in clinic. Results: In recent years, the government has taken a series of measures to deepen medical reform, and has begun special punish activity on the irrational use of antimicrobial drugs. Drugs used in Shanghai sample hospitals continue to grow up with delayed amplitude. The upward trend of anti-infective medication drugs was obviously kept within limits and its growth rate was far lower than others with first negative growth in 2011. The proportion for use of the third and fourth generation of cephalosporins and quinolones decreased while the ratio for use of penicillins and the first generation of cephalosporins increased, which showed a good development and the government measures worked. Conclusion: Anti-infective agents are one of the most commonly used drugs. Drug management and reasonable medication should be continueously strengthened so as to slow the emergence and development of bacterial resistance.