CAJ | 학술논문

目的:初步探讨血肝酶水平与血清 IL-22水平的相关情况.方法:对象为华山医院体检者454名,进行全面检查,采用 ELISA 方法检测 IL-22水平,采用 Spearman 等级分析 IL-22水平和肝酶的关系.结果:IL-22水平与谷丙转氨酶、谷草转氨酶及γ-谷氨酰转肽酶明显相关(相关系数分别为-0.122,-0.123及-0.127,P 值分别为0.020,0.019及0.015).结论:血清 IL-22水平与血肝酶水平显著负相关,提示 IL-22可能与肝脏疾病相关.
목적:초보탐토혈간매수평여혈청 IL-22수평적상관정황.방법:대상위화산의원체검자454명,진행전면검사,채용 ELISA 방법검측 IL-22수평,채용 Spearman 등급분석 IL-22수평화간매적관계.결과:IL-22수평여곡병전안매、곡초전안매급γ-곡안선전태매명현상관(상관계수분별위-0.122,-0.123급-0.127,P 치분별위0.020,0.019급0.015).결론:혈청 IL-22수평여혈간매수평현저부상관,제시 IL-22가능여간장질병상관.
Objective: To evaluate the association of liver enzyme levels with serum IL-22 levels. Method: Four hundred and fifty four physical examination subjects were enrolled in Huashan Hospital, and completed a comprehensive examination including IL-22 by ELISA method and the relationship between IL-22 levels and liver enzymes was analyzed by Spearman rank correlation. Result: IL-22 levels were significantly negatively correlated with alanine aminotransferase(ALT), aspartate aminotransferase(AST) and gamma-glutamyl transpeptidase (GGT) (correlation coefficients were -0.122, -0.123 and-0.127, Pvalues were 0.020, 0.019 and 0.015). Conclusion: These results suggested that IL-22 might be associated with liver diseases.