CAJ | 학술논문

干扰素是一种具有广泛生物学活性的细胞因子,不仅具有抗病毒作用,而且具有增强机体抗肿瘤免疫反应、抑制肿瘤血管生成、抗细胞增殖以及诱导细胞分化、凋亡等作用.干扰素家族包括α,β,γ三类,大量研究结果显示,α干扰素可以预防慢性病毒性肝炎患者中肝癌的发生,并且具有推迟肝细胞癌术后复发及抗肝癌侵袭和转移的作用,在临床实践中有着广泛的应用.
간우소시일충구유엄범생물학활성적세포인자,불부구유항병독작용,이차구유증강궤체항종류면역반응、억제종류혈관생성、항세포증식이급유도세포분화、조망등작용.간우소가족포괄α,β,γ삼류,대량연구결과현시,α간우소가이예방만성병독성간염환자중간암적발생,병차구유추지간세포암술후복발급항간암침습화전이적작용,재림상실천중유착엄범적응용.
Interferon is a cytokine with a wide range of biological activity, which has not only the antiviral activity, but also the roles of enhancing the body’s anti-tumor immune response, inhibiting tumor angiogenesis, anti-proliferation and inducing differentiation and apoptosis. The interferon family includes three categories ofα,β, andγ. A large number of studies have shown that interferonαcan prevent the occurrence of liver cancer in patients with chronic viral hepatitis, and has the roles of postponing liver cancer recurrence after surgical resection and inhibiting hepatocellular carcinoma invasion and metastasis, which has a wide application in clinical practice.