世界最新医学信息文摘（电子版）
世界最新醫學信息文摘（電子版）
세계최신의학신식문적（전자판）
World Latest Medicine Information
2012年
10期
7-8
,共2页
小剂量%咪达唑仑%芬太尼%局部麻醉%疗效%安全性
小劑量%咪達唑崙%芬太尼%跼部痳醉%療效%安全性
소제량%미체서륜%분태니%국부마취%료효%안전성
small dose midazolam fentanyl%local anesthesia%efficacy%safety
目的探讨小剂量咪达唑仑联合芬太尼用于局部麻醉的临床疗效及安全性.方法回顾性分析2011.8~2012.6间我院收治的52例行局部麻醉手术患者的临床资料,咪达唑仑与芬太尼首次剂量分别为0.05mg·kg-1、0.25μg·kg-1;维持剂量分别为0.1mg·kg-1·h-1、0.20μg·kg-1·h-1.结果术中及术后超过90%的患者镇静效果评分在3级以上;用药后dBP与sBP与用药前比较,无显著差异(P>0.05),而呼吸频率、Hr及spo2与用药前比较,差异有统计学意义(P<0.05);不良反应发生较少.结论在局部麻醉手术中采用小剂量咪达唑仑联合芬太尼疗效理想,安全性较高,值得临床推广.
目的探討小劑量咪達唑崙聯閤芬太尼用于跼部痳醉的臨床療效及安全性.方法迴顧性分析2011.8~2012.6間我院收治的52例行跼部痳醉手術患者的臨床資料,咪達唑崙與芬太尼首次劑量分彆為0.05mg·kg-1、0.25μg·kg-1;維持劑量分彆為0.1mg·kg-1·h-1、0.20μg·kg-1·h-1.結果術中及術後超過90%的患者鎮靜效果評分在3級以上;用藥後dBP與sBP與用藥前比較,無顯著差異(P>0.05),而呼吸頻率、Hr及spo2與用藥前比較,差異有統計學意義(P<0.05);不良反應髮生較少.結論在跼部痳醉手術中採用小劑量咪達唑崙聯閤芬太尼療效理想,安全性較高,值得臨床推廣.
목적탐토소제량미체서륜연합분태니용우국부마취적림상료효급안전성.방법회고성분석2011.8~2012.6간아원수치적52례행국부마취수술환자적림상자료,미체서륜여분태니수차제량분별위0.05mg·kg-1、0.25μg·kg-1;유지제량분별위0.1mg·kg-1·h-1、0.20μg·kg-1·h-1.결과술중급술후초과90%적환자진정효과평분재3급이상;용약후dBP여sBP여용약전비교,무현저차이(P>0.05),이호흡빈솔、Hr급spo2여용약전비교,차이유통계학의의(P<0.05);불량반응발생교소.결론재국부마취수술중채용소제량미체서륜연합분태니료효이상,안전성교고,치득림상추엄.
Objective to investigate the small dose of midazolam combined with fentanyl used for local anesthesia clinical curative effect and safety. Methods a retrospective analysis of 2011.8-2012.6 in our hospital 52 cases of local anesthesia opera-tion in patients with clinical data,midazolam and fentanyl first dose is respectively 0.05mg·kg-1,0.25μg·kg-1;the maintenance dose was 0.1mg·kg-1·H-1,0.20μg·kg-1·h-1. Results the intraoperative and postoperative more than 90%of patients with sedative effect score at level 3 or above;after administration of dBP and sBP compared with that before medication,no significant dif-ference (P>0.05),and respiratory frequency,Hr and spo2 compared with that before medication,the difference was statisti-cally significant (P<0.05);adverse reaction occurred less. conclusion:in the operation under local anesthesia with small dose of midazolam combined with fentanyl curative effect,high safety,worthy of clinical application.
