CAJ | 학술논문

目的了解白血病患者HBV和HCV感染状况.方法采用ELISA法检测256例白血病患者和377例骨折患者血清HBV标志物和抗-HCV.结果在256例白血病患者中有28例(10.9%)HBsAg阳性,显著高于骨折患者的5.6%(P<0.01);急性髓性白血病(AML)和慢性淋巴细胞性白血病(CLL)患者血清HBsAg阳性率分别为10.9%和33.3%,显著高于骨折人群(P<0.05).结论白血病患者HBV感染率较普通住院患者高, HBV感染与白血病的发生是否具有相关性,仍需进一步大样本研究.
목적료해백혈병환자HBV화HCV감염상황.방법채용ELISA법검측256례백혈병환자화377례골절환자혈청HBV표지물화항-HCV.결과재256례백혈병환자중유28례(10.9%)HBsAg양성,현저고우골절환자적5.6%(P<0.01);급성수성백혈병(AML)화만성림파세포성백혈병(CLL)환자혈청HBsAg양성솔분별위10.9%화33.3%,현저고우골절인군(P<0.05).결론백혈병환자HBV감염솔교보통주원환자고, HBV감염여백혈병적발생시부구유상관성,잉수진일보대양본연구.
Objective The aim of this study was to determine the carring rates of hepatitis B virus in patients with leukaemia. Methods ELISA was used for detection of HBV markers in serum in 256 patients with leukaemia and in 377 with bone fracture. Result The serum hepatitis B surface antigen (HBsAg) positivity rate was significantly higher in leukaemia group (10.9% vs 5.6%,P<0.01) than in control group; The serum HBsAg positive rates in acute myeloid leukemia and chronic lymphocytic leukemia patients were 10.9% and 33.3%, significantly higher than that in the control group (P<0.05). Conclusions The prevalence of hepatitis B viral infection is higher in leukaemia than in control group,and further study should be conducted to confirm the correlation between HBV infection and leukaemia.