CAJ | 학술논문

为探究稀土水杨酸8-羟基喹啉三元配合物RE(sal)2 hq(RE=Pr、Gd)对大肠杆菌的抑菌效果.实验采用杯碟法和二倍稀释法,通过测量抑菌圈直径探讨了两种配合物及其配体的抑菌能力.结果表明:配体8-羟基喹啉、配合物RE (sal)2 hq(RE=Pr、Gd)都具有很好的抑菌效果,而配体水杨酸及稀土(RE= Pr、Gd)离子抑菌效果都不明显.配合物Pr (sal)2 hq、Gd(sal)2 hq和配体8-羟基喹啉的最小抑菌浓度MIC值分别为:0.5 mmol/L、1 mmol/L和1 mmol/L .最小杀菌浓度MBC值分别为:4 mmol/L、5 mmol/L和14 mmol/L .初步推测稀土水杨酸8-羟基喹啉三元配合物可以作为药物运用于有害大肠杆菌的防治中.
위탐구희토수양산8-간기규람삼원배합물RE(sal)2 hq(RE=Pr、Gd)대대장간균적억균효과.실험채용배설법화이배희석법,통과측량억균권직경탐토료량충배합물급기배체적억균능력.결과표명:배체8-간기규람、배합물RE (sal)2 hq(RE=Pr、Gd)도구유흔호적억균효과,이배체수양산급희토(RE= Pr、Gd)리자억균효과도불명현.배합물Pr (sal)2 hq、Gd(sal)2 hq화배체8-간기규람적최소억균농도MIC치분별위:0.5 mmol/L、1 mmol/L화1 mmol/L .최소살균농도MBC치분별위:4 mmol/L、5 mmol/L화14 mmol/L .초보추측희토수양산8-간기규람삼원배합물가이작위약물운용우유해대장간균적방치중.
@@@@To study the antibacterial effects of ternary rare earth complexes with salicylic acid and 8 -hydroxy-lquinoline on Escherichia coli .This experiment adopted cylinder plate method and double -dilution method to ex-plore the antibacterial effects of the ternary complexes of RE (sal)2 hq(RE= Pr ,Gd) and their ligand on Es-cherichia coli ,by measuring ACD .The result showed that the ligand of 8-hydroxylquinoline and complexes of RE(sal)2 hq(RE=Pr ,Gd) had good antibacterial effect ,respectively .But the antibacterial effects of the ligand of salicylic acid and rare earth ions (RE=Pr ,Gd) were not obvious .We determined that the minimum inhibitory concentrations (MIC) of RE(sal)2 hq (RE=Pr ,Gd) and 8-hydroxylquinoline were 0 .5 mmol/L ,1 mmol/L and 1 mmol/L ,respectively .The minimum bactericidal concentrations (MBC) were 4 mmol/L ,5 mmol/L and 14 mmol/L ,respectively .We preliminarily speculated that RE(sal)2 hq (RE=Pr ,Gd) can apply in the prevention and control of harmful Escherichia coli .