CAJ | 학술논문

目的评价围手术期胰岛素泵治疗与多次皮下注射胰岛素治疗的效果.方法2型糖尿病患者合并股骨颈骨折32例、股骨转子间骨折18例,随机分为胰岛素泵治疗组(CSII组)26例与多次皮下注射胰岛素组(MDII组)24例,测定两组患者血脂、肝肾功能和C肽水平,进行多点血糖监测,评价两种治疗方法在血糖控制和胰岛素用量方面的差异.结果在年龄、病程、BMI、C-肽、空腹血糖、血脂、肝肾功等方面,两组无显著性差异(P均>0.05).与MDII组相比较,血糖达标时CSII组空腹血糖水平更低(P<0.05),每日胰岛素总量/体重、基础量/每日胰岛素总量及餐前量/每日胰岛素总量更少(P均<0.05),低血糖和严重低血糖发生例数更少.结论围手术期胰岛素泵治疗较传统多次皮下胰岛素注射治疗,血糖控制更加平稳、低血糖反应更少、胰岛素用量更少.
목적평개위수술기이도소빙치료여다차피하주사이도소치료적효과.방법2형당뇨병환자합병고골경골절32례、고골전자간골절18례,수궤분위이도소빙치료조(CSII조)26례여다차피하주사이도소조(MDII조)24례,측정량조환자혈지、간신공능화C태수평,진행다점혈당감측,평개량충치료방법재혈당공제화이도소용량방면적차이.결과재년령、병정、BMI、C-태、공복혈당、혈지、간신공등방면,량조무현저성차이(P균>0.05).여MDII조상비교,혈당체표시CSII조공복혈당수평경저(P<0.05),매일이도소총량/체중、기출량/매일이도소총량급찬전량/매일이도소총량경소(P균<0.05),저혈당화엄중저혈당발생례수경소.결론위수술기이도소빙치료교전통다차피하이도소주사치료,혈당공제경가평은、저혈당반응경소、이도소용량경소.
Objective To evaluate insulin pump and multiple daily insulin injection in perioperative type 2 diabetes accompanied with fracture.Methods Fifty cases of type 2 diabetes patients,32 cases accopanied with femoral neck fracture and 18 cases with femoral intertrochanteric fracture ,were randomly divided into insulin pump treatment group(CSII group)(n=26) and multiple daily insulin injections group (MDII group)(n=24).The blood ketone and lipid analysis,liver and kidney function and c-peptide levels were measured.Finger blood glucose was monitored seven times a day,hypoglycemia was recorded and insulin dosage was evaluated when blood glucose reached the goal .Results No difference was found in age,history,body mass index,c-peptide,blood lipid,fasting plasma blood glucose,liver function and kidney function between the two groups (P>0.05).Compared with MDII group,fasting blood glucose was lower when reached the operation goals(P<0.05).Compared with MDII group,daily overall dose of insulin/weight,bas-al/overall dosage of insulin and bolus/overall dosage of insulin was significantly lower than MDII group (P<0.05). Conclusion Compared with MDII,blood sugar was more stable,the hypoglycemia was less in CSII group .Less dose of insulin was used in CSII group than that of MDII group .