CAJ | 학술논문

目的观察全程中医特色健康指导对冠心病慢性心衰(CHF)患者血浆N端脑钠肽前体(NT-proBNP)及心力贮备的影响.方法符合NYHA心功能分级Ⅱ~Ⅲ级的共100例老年冠心病心衰患者随机分为对照组和试验组,在常规西药基础上分别给予常规健康指导或全程中医特色健康指导,比较两组在6个月、12个月时血浆NT-proBNP水平及对心力贮备(6min步行试验成绩)的影响.结果两组干预6个月、12个月后,血浆NT-proBNP水平均明显下降(P<0.05),治疗12个月后试验组的影响较对照组更显著(P<0.05).对照组的6min步行试验成绩干预前后无明显变化(P>0.05),试验组6min步行试验成绩在干预6个月及12个月后逐步提高(P<0.05).结论在常规药物治疗基础上全程中医特色健康指导能更好地减轻CHF患者心衰程度,增强心力贮备,是CHF患者有效的健康管理模式.
목적관찰전정중의특색건강지도대관심병만성심쇠(CHF)환자혈장N단뇌납태전체(NT-proBNP)급심력저비적영향.방법부합NYHA심공능분급Ⅱ~Ⅲ급적공100례노년관심병심쇠환자수궤분위대조조화시험조,재상규서약기출상분별급여상규건강지도혹전정중의특색건강지도,비교량조재6개월、12개월시혈장NT-proBNP수평급대심력저비(6min보행시험성적)적영향.결과량조간예6개월、12개월후,혈장NT-proBNP수평균명현하강(P<0.05),치료12개월후시험조적영향교대조조경현저(P<0.05).대조조적6min보행시험성적간예전후무명현변화(P>0.05),시험조6min보행시험성적재간예6개월급12개월후축보제고(P<0.05).결론재상규약물치료기출상전정중의특색건강지도능경호지감경CHF환자심쇠정도,증강심력저비,시CHF환자유효적건강관리모식.
Objective To observe the effects of health guidance with characteristics of traditional Chinese medicine (TCM) on the elderly coronary heart disease(CHD) patients with chronic heart failure (CHF).Methods One hundred elderly patients with CHD were chosen as the subjects,whose heart function were in line with the heart functional class programⅡ-Ⅲlevel of NYHA.The patients were ran-domly divided into control group and test group .On the basic treatment of conventional western medicine ,the control group was given the com-mon health guidance,while the test group was given health guidance with characteristics of TCM .At the beginning of the study,after 6 and 12 months of therapy,the level of plasma N-terminal brain natriuretic peptide precursor (NT-proBNP) and cardiac reserve(tested by 6-minute walk test scores) were evaluated respectively.Results Compared with the base line,there were significant decreases in the NT-proBNP in both groups(P<0.05).There was no significant difference on 6-minute walk test scores in the control group through the study (P>0.05). After 12 months of treatment the effects of the test group on NT-proBNP and 6-minute walk test scores were more pronounced than the control group(P<0.05).Conclusion Health guidance with characteristics of TCM could improve heart function and cardiac reserve function better than the common health guidance in CHF patients ,which is an effective health management mode of CHF .