CAJ | 학술논문

背景:羟基磷灰石生物陶瓷以天然优质海洋珊瑚为原料,在珊瑚骨架上形成羟基磷灰石薄层,保留珊瑚天然孔孔相同的支架结构,为组织生长提供了良好空间.目的:观察羟基磷灰石生物陶瓷膜引导骨再生修复牙周骨缺损的临床效果.方法:将42例下颌第一磨牙牙周病致骨缺损患者随机分组:实验组采用羟基磷灰石生物陶瓷结合口腔修复膜充填修复骨缺损,对照组采用单独羟基磷灰石生物陶瓷充填修复.结果与结论:临床随访观察12个月,两组牙周组织附着丧失、牙周探诊深度较治疗前明显改善(P<0.05),且实验组牙周组织附着丧失、牙周探诊深度改善优于对照组(P<0.05);实验组骨缺损区新骨形成密度和骨量均优于对照组(P<0.05).表明采用羟基磷灰石生物陶瓷充填骨缺损区同时覆盖生物膜的引导骨再生技术可获得良好的骨引导再生效果,修复骨缺损.
배경:간기린회석생물도자이천연우질해양산호위원료,재산호골가상형성간기린회석박층,보류산호천연공공상동적지가결구,위조직생장제공료량호공간.목적:관찰간기린회석생물도자막인도골재생수복아주골결손적림상효과.방법:장42례하합제일마아아주병치골결손환자수궤분조:실험조채용간기린회석생물도자결합구강수복막충전수복골결손,대조조채용단독간기린회석생물도자충전수복.결과여결론:림상수방관찰12개월,량조아주조직부착상실、아주탐진심도교치료전명현개선(P<0.05),차실험조아주조직부착상실、아주탐진심도개선우우대조조(P<0.05);실험조골결손구신골형성밀도화골량균우우대조조(P<0.05).표명채용간기린회석생물도자충전골결손구동시복개생물막적인도골재생기술가획득량호적골인도재생효과,수복골결손.
BACKGROUND:The coral ine hydroxyapatite is take high quality natural narine biological as raw materials. It forms hydroxyapatite thin layer in coral skeleton, so it keeps natural coral distributed framework, thereby providing a good space for tissue growth. OBJECTIVE:To investigate the clinical effect of coral ine hydroxyapatite on guiding bone regeneration for the repair of alveolar bone defects. METHODS:Forty-two patients with bone defects caused by mandibular first molar periodontitis were col ected and randomly divided into experimental group and control group. Patients in the experimental group were treated with coral ine hydroxyapatite combined with oral biofilm to fil and repair bone defects, and those in the control group were only treated with coral ine hydroxyapatite. RESULTS AND CONCLUSION:The patients were fol owed up for 12 months and the results showed that periodontal attachment loss was found in the two groups, besides, periodontal probing depth was improved obviously after treatment (P<0.05). In addition, compared with the control group, periodontal attachment loss and periodontal probing depth in the experimental group were better (P<0.05). Moreover, new bone formation density and bone mass of the experimental group were superior to those of the control group (P<0.05). These results suggest that coral ine hydroxyapatite combined with guided bone regeneration technique can have good effect on guiding bone regeneration and repair bone defects.