中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2012年
48期
8983-8987
,共5页
张晗%徐义明%万大千%白跃宏
張晗%徐義明%萬大韆%白躍宏
장함%서의명%만대천%백약굉
股骨%骨折%内固定%微波治疗%中频电疗
股骨%骨摺%內固定%微波治療%中頻電療
고골%골절%내고정%미파치료%중빈전료
背景:对骨折区域采用金属植入物进行内固定后,进行物理治疗且辅以康复训练是否可以促进骨折愈合?实验对此进行探索.目的:验证骨折金属植入物内固定后物理治疗的可行性,观察其对骨折愈合及周围组织的影响.方法:选取24只成年大白兔,随机分为3组.制作右侧股骨中段横断性骨折模型,并用钢板内固定.内固定后空白对照组不采取任何治疗;中频治疗组自内固定后第4天起,连续30 d 采用电脑中频治疗仪 ECM99-IIB 治疗;高频治疗组自内固定后第4天起,连续30 d 采用微波治疗仪 PM-800S 进行治疗.结果与结论:大体观察所见空白对照组纤维组织最多,中频治疗组次之,高频治疗组最少.神经传导速度3组间比较差异无显著性意义(P >0.05).组织学观察空白对照组未见明显骨基质,中频治疗组可见形成中骨小梁,高频治疗组可见较为成熟的骨小梁.空白对照组肌肉组织大量纤维化,中频治疗组肌肉组织可见部分纤维化,高频治疗组纤维化程度最低.血清生化指标结果显示 Ca2+和碱性磷酸酶指标高频治疗组、中频治疗组显著高于空白对照组(P <0.05).结果表明,高频电疗及中频电疗法可应用于股骨骨折内固定后,且对于骨折的修复具有促进作用,高频治疗的效果优于中频治疗.
揹景:對骨摺區域採用金屬植入物進行內固定後,進行物理治療且輔以康複訓練是否可以促進骨摺愈閤?實驗對此進行探索.目的:驗證骨摺金屬植入物內固定後物理治療的可行性,觀察其對骨摺愈閤及週圍組織的影響.方法:選取24隻成年大白兔,隨機分為3組.製作右側股骨中段橫斷性骨摺模型,併用鋼闆內固定.內固定後空白對照組不採取任何治療;中頻治療組自內固定後第4天起,連續30 d 採用電腦中頻治療儀 ECM99-IIB 治療;高頻治療組自內固定後第4天起,連續30 d 採用微波治療儀 PM-800S 進行治療.結果與結論:大體觀察所見空白對照組纖維組織最多,中頻治療組次之,高頻治療組最少.神經傳導速度3組間比較差異無顯著性意義(P >0.05).組織學觀察空白對照組未見明顯骨基質,中頻治療組可見形成中骨小樑,高頻治療組可見較為成熟的骨小樑.空白對照組肌肉組織大量纖維化,中頻治療組肌肉組織可見部分纖維化,高頻治療組纖維化程度最低.血清生化指標結果顯示 Ca2+和堿性燐痠酶指標高頻治療組、中頻治療組顯著高于空白對照組(P <0.05).結果錶明,高頻電療及中頻電療法可應用于股骨骨摺內固定後,且對于骨摺的脩複具有促進作用,高頻治療的效果優于中頻治療.
배경:대골절구역채용금속식입물진행내고정후,진행물리치료차보이강복훈련시부가이촉진골절유합?실험대차진행탐색.목적:험증골절금속식입물내고정후물리치료적가행성,관찰기대골절유합급주위조직적영향.방법:선취24지성년대백토,수궤분위3조.제작우측고골중단횡단성골절모형,병용강판내고정.내고정후공백대조조불채취임하치료;중빈치료조자내고정후제4천기,련속30 d 채용전뇌중빈치료의 ECM99-IIB 치료;고빈치료조자내고정후제4천기,련속30 d 채용미파치료의 PM-800S 진행치료.결과여결론:대체관찰소견공백대조조섬유조직최다,중빈치료조차지,고빈치료조최소.신경전도속도3조간비교차이무현저성의의(P >0.05).조직학관찰공백대조조미견명현골기질,중빈치료조가견형성중골소량,고빈치료조가견교위성숙적골소량.공백대조조기육조직대량섬유화,중빈치료조기육조직가견부분섬유화,고빈치료조섬유화정도최저.혈청생화지표결과현시 Ca2+화감성린산매지표고빈치료조、중빈치료조현저고우공백대조조(P <0.05).결과표명,고빈전료급중빈전요법가응용우고골골절내고정후,차대우골절적수복구유촉진작용,고빈치료적효과우우중빈치료.
BACKGROUND: After fracture fixation with metal implants, is it able to take physical therapy in promoting the fracture? This exploratory experiment can be the preparation for later discussion. OBJECTIVE: To investigate the feasibility of physical therapy after fracture fixation with metal implants and to observe the effect of physical therapy on the fracture recovery and surrounding tissues. METHODS: Twenty-four adult white rabbits were selected and randomly divided into three groups. The models of the transaction fracture on the middle of left femur were established and fixed with plate. After fixation, the models in the control group received no treatment; the models in the intermediate-frequency group received the intermediate-frequency electro-therapy with intermediate-frequency therapeutic equioment ECM99-IIB at 4 days after fixation and lasted for 30 days; the models in the high-frequency group received the microwave therapy with microwave apparatus PM-800S at 4 days after fixation and lasted for 30 days. RESULTS AND CONCLUSION: General observation showed that the control group had the most fibrous tissue, fol owed by the intermediate-frequency group, and high-frequency group had the least fibrous tissue. There was no significant difference of nerve conduction velocity among three groups (P > 0.05). Histological observation showed that there was no visible bone matrix in the control group, trabecular bone formation could be seen in the intermediate-frequency group, maturate trabecular bone could be seen in the high-frequency group. Fibrosis of muscle tissue could be seen in the control group, partly fibrosis of muscle tissue could be seen in the intermediate-frequency group and the fibrosis in the high-frequency group was not obvious. Serum biochemical indicators showed that the serum content of Ca2+ and alkaline phosphatase in the intermediate-frequency group and high-frequency group were significantly higher than those in the control group (P < 0.05). Under the experimental conditions, intermediate-frequency electro-therapy and high-frequency electro-therapy could be used after fracture fixation, and had a positive effect on the union of fracture. The effect of the high-frequency electro-therapy was better than that of the intermediate-frequency electro-therapy.