中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2012年
52期
9744-9749
,共6页
谭远超%周纪平%闫虎%张恩忠%张秋玲
譚遠超%週紀平%閆虎%張恩忠%張鞦玲
담원초%주기평%염호%장은충%장추령
动态应力钢板%磁共振%骨折愈合%X射线%羊%AO钢板%股骨干骨析%植入体
動態應力鋼闆%磁共振%骨摺愈閤%X射線%羊%AO鋼闆%股骨榦骨析%植入體
동태응력강판%자공진%골절유합%X사선%양%AO강판%고골간골석%식입체
背景:目前钢板内固定治疗骨折愈合出现应力遮挡影响骨折愈合.
目的:观察动态应力钢板(CO钢板)与普通应力钢板(AO钢板)治疗羊股骨干骨折愈合的效果.
方法:24只山羊制备股骨干骨折模型,造模后随机分为2组,AO钢板组和CO钢板组分别用AO、CO钢板内固定,分别在1,2,3周取出股骨,常规行X射线与磁共振扫描.
结果与结论:X射线显示1周时,两组钢板骨折断端均未见明显变化,骨折线清晰可见;2周AO钢板组骨折断端无明显变化,骨折线明显,CO钢板组骨折断端骨密度增高,骨折线开始变模糊;3周AO钢板组骨折断端骨密度增加, CO钢板组骨折断端骨密度继续增高,出现云絮状外骨痂.MRI显示1周时,两组钢板骨折断端T1WI呈高信号,T2WI压脂序列上呈低信号,但AO钢板组骨折断端PDIR-TSE呈低信号,CO钢板组呈高信号.2周时两组骨折断端T1WI呈等或高信号,在T2WI压脂序列上呈等或低信号,AO钢板组PDIR-TSE呈低信号,CO钢板组呈高信号.3周AO钢板组可见骨折线明显,骨折断端在T1WI呈等或低信号,在T2WI压脂序列上呈等低信号,PDIR-TSE呈低信号;CO 钢板组骨折断端可见骨折线模糊,骨折断段在 T1WI 上呈等或高信号,在 T2WI 压脂序列上呈等或低信号, PDIR-TSE呈等或高信号.提示CO钢板组骨折断端的血液循环、骨痂含量均优于AO钢板组骨折断端.
揹景:目前鋼闆內固定治療骨摺愈閤齣現應力遮擋影響骨摺愈閤.
目的:觀察動態應力鋼闆(CO鋼闆)與普通應力鋼闆(AO鋼闆)治療羊股骨榦骨摺愈閤的效果.
方法:24隻山羊製備股骨榦骨摺模型,造模後隨機分為2組,AO鋼闆組和CO鋼闆組分彆用AO、CO鋼闆內固定,分彆在1,2,3週取齣股骨,常規行X射線與磁共振掃描.
結果與結論:X射線顯示1週時,兩組鋼闆骨摺斷耑均未見明顯變化,骨摺線清晰可見;2週AO鋼闆組骨摺斷耑無明顯變化,骨摺線明顯,CO鋼闆組骨摺斷耑骨密度增高,骨摺線開始變模糊;3週AO鋼闆組骨摺斷耑骨密度增加, CO鋼闆組骨摺斷耑骨密度繼續增高,齣現雲絮狀外骨痂.MRI顯示1週時,兩組鋼闆骨摺斷耑T1WI呈高信號,T2WI壓脂序列上呈低信號,但AO鋼闆組骨摺斷耑PDIR-TSE呈低信號,CO鋼闆組呈高信號.2週時兩組骨摺斷耑T1WI呈等或高信號,在T2WI壓脂序列上呈等或低信號,AO鋼闆組PDIR-TSE呈低信號,CO鋼闆組呈高信號.3週AO鋼闆組可見骨摺線明顯,骨摺斷耑在T1WI呈等或低信號,在T2WI壓脂序列上呈等低信號,PDIR-TSE呈低信號;CO 鋼闆組骨摺斷耑可見骨摺線模糊,骨摺斷段在 T1WI 上呈等或高信號,在 T2WI 壓脂序列上呈等或低信號, PDIR-TSE呈等或高信號.提示CO鋼闆組骨摺斷耑的血液循環、骨痂含量均優于AO鋼闆組骨摺斷耑.
배경:목전강판내고정치료골절유합출현응력차당영향골절유합.
목적:관찰동태응력강판(CO강판)여보통응력강판(AO강판)치료양고골간골절유합적효과.
방법:24지산양제비고골간골절모형,조모후수궤분위2조,AO강판조화CO강판조분별용AO、CO강판내고정,분별재1,2,3주취출고골,상규행X사선여자공진소묘.
결과여결론:X사선현시1주시,량조강판골절단단균미견명현변화,골절선청석가견;2주AO강판조골절단단무명현변화,골절선명현,CO강판조골절단단골밀도증고,골절선개시변모호;3주AO강판조골절단단골밀도증가, CO강판조골절단단골밀도계속증고,출현운서상외골가.MRI현시1주시,량조강판골절단단T1WI정고신호,T2WI압지서렬상정저신호,단AO강판조골절단단PDIR-TSE정저신호,CO강판조정고신호.2주시량조골절단단T1WI정등혹고신호,재T2WI압지서렬상정등혹저신호,AO강판조PDIR-TSE정저신호,CO강판조정고신호.3주AO강판조가견골절선명현,골절단단재T1WI정등혹저신호,재T2WI압지서렬상정등저신호,PDIR-TSE정저신호;CO 강판조골절단단가견골절선모호,골절단단재 T1WI 상정등혹고신호,재 T2WI 압지서렬상정등혹저신호, PDIR-TSE정등혹고신호.제시CO강판조골절단단적혈액순배、골가함량균우우AO강판조골절단단.
BACKGROUND:Stress shielding can influence the healing of fracture in the treatment of fracture healing by plate fixation. @@@@OBJECTIVE:To observe the effect of dynamic stress plate (CO plate) and the normal stress plate (AO plate) on sheep femoral shaft fracture healing. @@@@METHODS:Twenty-four healthy adult sheep were prepared for establishing the femoral shaft fracture model. After modeling, the models were divided into two groups:AO plate group and CO plate group. The fractures in the two groups were fixed with AO and CO plate respectively. The femurs with the internal fixation were picked out at 1, 2 and 3 weeks;conventional X-ray and MRI scanning were performed. @@@@RESULTS AND CONCLUSION:X-ray film showed that there was no significant change at the fracture broken ends in two groups, and the fracture line was clear at 1 week after fixation;at 2 weeks after fixation, there was no significant change at the fracture broken end in AO plate group and the fracture line was clear, while in the CO plate group, the bone mineral density at the fracture broken end was increased and the fracture line began to blur;at 3 weeks after fixation, the bone mineral density at the fracture broken end in the AO plate group was increased, the bone mineral density in the CO plate group was increased continuously with the cloud-shaped external cal us. MRI scanning showed that at 1 week after fixation, the T1 weighted imaging of the fracture broken end in two groups presented a high signal and the T2 weighted imaging on the fat saturation sequence presented a low signal, but the PDIR-TSE of the fracture broken end in the AO plate group showed a low signal and showed a high signal in CO plate group;at 2 weeks after fixation, T1 weighted imaging of the fracture broken end in two groups presented an equal or higher signal and the T2 weighted imaging on the fat saturation sequence presented a equal or lower signal, while the PDIR-TSE of the fracture broken end in the AO plate group showed a low signal and showed a high signal in CO plate group;at 3 weeks after fixation in the AO plate group, clearly fracture line could be seen, the T1 weighted imaging of the fracture broken end presented an equal or lower signal and the T2 weighted imaging on the fat saturation sequence presented an equal or lower signal, while the PDIR-TSE of the fracture broken end showed a low signal;at 3 weeks after fixation in the CO plate group, the fracture line at the fracture broken end was blur, the T1 weighted imaging of the fracture broken end presented an equal or higher signal and the T2 weighted imaging on the fat saturation sequence presented an equal or lower signal, while the PDIR-TSE of the fracture broken end showed an equal or higher signal. The blood circulation and the bone cal us content at the fracture broken end in the CO plate group were higher than those in the AO plate group.
