CAJ | 학술논문

背景:对于经皮椎体成形治疗骨质疏松性椎体骨折研究多基于新鲜性骨质疏松性椎体压缩性骨折,而对陈旧性老年骨质疏松性椎体骨折的治疗鲜有报道. 目的:评价经皮椎体成形治疗陈旧性老年骨质疏松性椎体骨折的疗效. 方法:纳入2007年1月至2010年12月上海交通大学医学院附属仁济医院收治的陈旧性老年骨质疏松性椎体骨折患者,所有12例患者(14椎)均采经皮椎体成形治疗.记录患者经皮椎体成形前、经皮椎体成形后1个月和1年时的疼痛目测类比评分、Oswestry功能障碍索引和站立位侧位片病椎Cobb角. 结果与结论:所有陈旧性老年骨质疏松性椎体骨折患者未发生感染、肺栓塞、骨水泥毒性反应和骨水泥渗漏而造成的神经压迫症状等并发症.经皮椎体成形后失访1例,死亡1例,死亡原因与手术无关.陈旧性老年骨质疏松性椎体骨折患者经皮椎体成形后疼痛目测类比评分和 Oswestry 功能障碍索引评分均显著低于经皮椎体成形前(P <0.01),而经皮椎体成形前后患者病椎Cobb角差异无显著性意义(P>0.05).提示经皮椎体成形能明显缓解陈旧性骨质疏松性椎体骨折患者的疼痛、改善了患者的生活质量.
배경:대우경피추체성형치료골질소송성추체골절연구다기우신선성골질소송성추체압축성골절,이대진구성노년골질소송성추체골절적치료선유보도. 목적:평개경피추체성형치료진구성노년골질소송성추체골절적료효. 방법:납입2007년1월지2010년12월상해교통대학의학원부속인제의원수치적진구성노년골질소송성추체골절환자,소유12례환자(14추)균채경피추체성형치료.기록환자경피추체성형전、경피추체성형후1개월화1년시적동통목측류비평분、Oswestry공능장애색인화참립위측위편병추Cobb각. 결과여결론:소유진구성노년골질소송성추체골절환자미발생감염、폐전새、골수니독성반응화골수니삼루이조성적신경압박증상등병발증.경피추체성형후실방1례,사망1례,사망원인여수술무관.진구성노년골질소송성추체골절환자경피추체성형후동통목측류비평분화 Oswestry 공능장애색인평분균현저저우경피추체성형전(P <0.01),이경피추체성형전후환자병추Cobb각차이무현저성의의(P>0.05).제시경피추체성형능명현완해진구성골질소송성추체골절환자적동통、개선료환자적생활질량.
BACKGROUND:The researches on the treatment of osteoporotic vertebral fractures by percutaneous vertebroplasty are mainly based on the fresh osteoporotic compression vertebral fractures, and the reports on the treatment of old symptomatic osteoporotic vertebral fractures are rare. @@@@OBJECTIVE:To investigate the effect of percutaneous vertebroplasty in the treatment of old symptomatic osteoporotic vertebral fractures in elderly. @@@@METHODS:The patients with old symptomatic osteoporotic vertebral fractures in elderly were selected from Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine during January 2007 to December 2010, and al the 12 patients (14 vertebras) were treated with percutaneous vertebroplasty. The Visual Analogue Scale score, Oswestry disability index and local sagittal Cobb’s angles were measured before percutaneous vertebroplasty, and 1 month and 1 year after percutaneous vertebroplasty. @@@@RESULTS AND CONCLUSION:There was no infection, toxic effect of bone cement, pulmonary embolism or leakage of bone cement in the patients with old symptomatic osteoporotic vertebral fractures. After percutaneous vertebroplasty, there was one case with loss of fol ow-up, one case of death, and the death has nothing to do with the surgery. The Visual Analogue Scale score and Oswestry disability index of the patients with old symptomatic osteoporotic vertebral fractures after percutaneous vertebroplasty were significantly lower than those before percutaneous vertebroplasty (P<0.01), and there was no significant difference of local sagittal Cobb’s angles before and after percutaneous vertebroplasty (P>0.05). It suggests that percutaneous vertebroplasty can relieve the pain and improve the life quality of the patients with old symptomatic osteoporotic vertebral fractures.