医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2012年
29期
113-114
,共2页
布洛芬注射液%局部毒性
佈洛芬註射液%跼部毒性
포락분주사액%국부독성
Caldolor%Local Toxicity
目的观察布洛芬注射液的局部毒性.方法采用 BALB/c 小鼠、SD 大鼠、豚鼠、新西兰白兔观察局部毒性反应.结果布洛芬注射液全身主动过敏和被动皮肤过敏试验结果为阴性,对血管无刺激性,亦无溶血和红细胞凝集现象.结论布洛芬注射液用于临床是相对安全的.
目的觀察佈洛芬註射液的跼部毒性.方法採用 BALB/c 小鼠、SD 大鼠、豚鼠、新西蘭白兔觀察跼部毒性反應.結果佈洛芬註射液全身主動過敏和被動皮膚過敏試驗結果為陰性,對血管無刺激性,亦無溶血和紅細胞凝集現象.結論佈洛芬註射液用于臨床是相對安全的.
목적관찰포락분주사액적국부독성.방법채용 BALB/c 소서、SD 대서、돈서、신서란백토관찰국부독성반응.결과포락분주사액전신주동과민화피동피부과민시험결과위음성,대혈관무자격성,역무용혈화홍세포응집현상.결론포락분주사액용우림상시상대안전적.
Objective To evaluate local toxicity of Caldolor. Methods Local toxicity of Caldolor were observed on BLAB/c mice,SD rats,guinea-pigs and rabbits. Results The anaphylaxis was negative and there were no vascular irritation or no hemolysis. Conclusion Caldolor is a safe new agents.
