CAJ | 학술논문

目的探讨纳洛酮合用水溶性维生素治疗急性酒精中毒的疗效及实用性.方法将138例急性酒精中毒患者随机分为纳洛酮治疗组和纳洛酮合用维生素治疗组,治疗期间注意患者呼吸、脉搏、血压及神态变化,并观察其疗效.结果纳洛酮合用维生素治疗组的催醒时间明显少于单用纳洛酮治疗组,醒后头痛、头晕、电解质紊乱的发生率明显减少,两组治疗效果比较有显著性差异(P <0.05).结论纳洛酮合用水溶性维生素治疗急性酒精中毒的疗效明显优于单用纳洛酮,值得临床推广应用.
목적탐토납락동합용수용성유생소치료급성주정중독적료효급실용성.방법장138례급성주정중독환자수궤분위납락동치료조화납락동합용유생소치료조,치료기간주의환자호흡、맥박、혈압급신태변화,병관찰기료효.결과납락동합용유생소치료조적최성시간명현소우단용납락동치료조,성후두통、두훈、전해질문란적발생솔명현감소,량조치료효과비교유현저성차이(P <0.05).결론납락동합용수용성유생소치료급성주정중독적료효명현우우단용납락동,치득림상추엄응용.
Objective To investgate curative effects and practicality of naloxone combined with water-soluble vitamins in treating acute alcoholism. Methods 138 cases patients with acute severe alcoholism were randomly divided into two groups:the treatment group(n=69)which were given naloxone combined with water-soluble vitamins and the control group(n=69) which were given naloxone. Meanwhile, to pay attention to patients, respiratory, pulse, blood pressure and consciousness and observe curative effects. Results The safe consciousness time and symptoms disappearing time of the treatment group were remarkably shorter than those of control group, and the incidence rate of headache, dizziness and electrolyte disturbance after awakening was obviously low. The difference between two groups was statisticaly significant(P < 0.05).Conclusion the curative effect of naloxone combined with water-soluble vitamins in treating acute alcoholism is remarkably better than only using naloxone , so the therapy method is worthy of appling and popularizing in clinic.