CAJ | 학술논문

目的探索新药设计创新理论.方法研习自然法则,归纳、整理、桥接、整合传统药与现代药物设计之间的关系.结果结合科学天然药发展,创造性地提出科学天然药之药物设计——基于传统医药的启示和指引,结合现代药物设计的理论和成果,创造性地设计新结构,主要应用孪药设计、前药设计、软药设计等理论.结果科学天然药之药物设计可能是一条多快好省的创新药物设计之路,可以实现1+1+???> n 的结果.
목적탐색신약설계창신이론.방법연습자연법칙,귀납、정리、교접、정합전통약여현대약물설계지간적관계.결과결합과학천연약발전,창조성지제출과학천연약지약물설계——기우전통의약적계시화지인,결합현대약물설계적이론화성과,창조성지설계신결구,주요응용련약설계、전약설계、연약설계등이론.결과과학천연약지약물설계가능시일조다쾌호성적창신약물설계지로,가이실현1+1+???> n 적결과.
PURPOSE To explore the innovation theory of drug design. METHOD According to the study of the laws of nature, finding the relationship between the traditional medicine and modern drug design. RESULT Combined with the development of the science of natural medicine, creatively put forward the natural medicine drug design scientificaly - based on the inspiration and guidance of traditional Chinese medicine, combined with the theory of modern drug design and achievement, creatively design of the new structure, the main application includes twin drug design, prodrug design, soft drug design and so on. RESULT Scientificaly drug design of natural medicine may be a better way for drug design, we can achieve the result of 1+1+…>n