医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2012年
32期
125-126
,共2页
婴儿%新生儿%惊厥%病因%治疗%预后
嬰兒%新生兒%驚厥%病因%治療%預後
영인%신생인%량궐%병인%치료%예후
infant%neonatal%febrile eizures%etiology%treatmen-t%prognosis
目的探讨新生儿惊厥病因、临床特点及急救方法,减少惊厥及后遗症的发生.方法回顾性分析我院2005年01月-2011年12月共收治的148例惊厥新生儿的临床资料.结果痊愈121例,有症状出院的19例,死亡5例,自动出院3例,20例遗留有不同程度神经系统后遗症.围产期窒息是引起惊厥的首要原因,其次是感染性疾病、糖及电解质紊乱、各类先天性遗传代谢病.发作类型以微小性发作为多见,其次为阵挛性发作.治疗重点在于止痉,首选苯巴比妥,14.9%的患儿足量用药不能控制.结论围产期窒息是导致新生儿惊厥的主要病因;苯巴比妥仍是抗惊厥的首选药物,少数患儿须加用二线药物;发作形式以微小性发作最为多见;EEG 背景波是判断预后的一个良好的指示.
目的探討新生兒驚厥病因、臨床特點及急救方法,減少驚厥及後遺癥的髮生.方法迴顧性分析我院2005年01月-2011年12月共收治的148例驚厥新生兒的臨床資料.結果痊愈121例,有癥狀齣院的19例,死亡5例,自動齣院3例,20例遺留有不同程度神經繫統後遺癥.圍產期窒息是引起驚厥的首要原因,其次是感染性疾病、糖及電解質紊亂、各類先天性遺傳代謝病.髮作類型以微小性髮作為多見,其次為陣攣性髮作.治療重點在于止痙,首選苯巴比妥,14.9%的患兒足量用藥不能控製.結論圍產期窒息是導緻新生兒驚厥的主要病因;苯巴比妥仍是抗驚厥的首選藥物,少數患兒鬚加用二線藥物;髮作形式以微小性髮作最為多見;EEG 揹景波是判斷預後的一箇良好的指示.
목적탐토신생인량궐병인、림상특점급급구방법,감소량궐급후유증적발생.방법회고성분석아원2005년01월-2011년12월공수치적148례량궐신생인적림상자료.결과전유121례,유증상출원적19례,사망5례,자동출원3례,20례유류유불동정도신경계통후유증.위산기질식시인기량궐적수요원인,기차시감염성질병、당급전해질문란、각류선천성유전대사병.발작류형이미소성발작위다견,기차위진련성발작.치료중점재우지경,수선분파비타,14.9%적환인족량용약불능공제.결론위산기질식시도치신생인량궐적주요병인;분파비타잉시항량궐적수선약물,소수환인수가용이선약물;발작형식이미소성발작최위다견;EEG 배경파시판단예후적일개량호적지시.
Objective Investigate the cause of neonatal convulsions、clinical characteristics and first-aid methods,reduce the incidence of seizures and the sequelae.Methods Retrospective analysis of our hospital from Janu-ary 2005 to December 2011 in the total of 148 cases of eclampsia admitted to the clinical data of newborn.Results 121 cases of ful recovery,discharged from hospital with symptoms of 19 cases,the death of five cases, three cases of automatic discharge, there are 20 cases left over from the nervous system sequelae of varying degrees.Caused by perinatal asphyxia is the primary cause of febrile seizures, folowed by infectious diseases, sugar and electrolyte disorders, various types of congenital genetic metabolic diseases. Type of attack made little as often, folowed by clonic seizures. To stop focusing on the reatment of seizures, Phenobarbital prefered ,14.9% of children with a sufficient quantiy of medicines stil con not control.Conclusions Perinatal asphyxia is a major cause of neonatal convulsions;Phenobarbital is stil the first choice anticonvulsant drug, a smal number of children with second-line drugs should be added; The from of attack to the most minor seizures; EEG wave background is a good prognosis instructions.