CAJ | 학술논문

目的分析探讨肾嗜酸细胞腺瘤临床基本表现、病理学特点、影像学表现以及免疫表型,为肾嗜酸细胞腺瘤的临床诊断提供参照.方法选取2006年3月—2012年3月我院收治的7例肾嗜酸细胞腺瘤患者的临床资料,对患者的临床基本情况、病理学特点、影像学特点、免疫表型分别进行分析.结果7例患者中病变4例位于右侧,3例位于左侧;直径在2—11cm;6例进行全肾切除,1例直径2cm单纯肿块切除.巨检肿瘤呈现圆形,边界清晰,未见坏死和出血;镜检显示肿瘤细胞由大量的形态一致的圆形或多角形细胞组成,瘤细胞具有丰富的嗜酸性颗粒.3例经B超检查,显示低回声,回声规则,边界不清楚.7例均经CT检查,显示为肾实质内提示有圆形的组织肿块,强化明显.免疫组化显示AE1/AE3与EMA显示阳性,CK7与Vimentin显示为阴性.结论在肾嗜酸细胞腺瘤的诊断中,应将临床病理学与影像学、免疫表型结合进行综合分析,以提高诊断准确率,防止发生误诊.
목적분석탐토신기산세포선류림상기본표현、병이학특점、영상학표현이급면역표형,위신기산세포선류적림상진단제공삼조.방법선취2006년3월—2012년3월아원수치적7례신기산세포선류환자적림상자료,대환자적림상기본정황、병이학특점、영상학특점、면역표형분별진행분석.결과7례환자중병변4례위우우측,3례위우좌측;직경재2—11cm;6례진행전신절제,1례직경2cm단순종괴절제.거검종류정현원형,변계청석,미견배사화출혈;경검현시종류세포유대량적형태일치적원형혹다각형세포조성,류세포구유봉부적기산성과립.3례경B초검사,현시저회성,회성규칙,변계불청초.7례균경CT검사,현시위신실질내제시유원형적조직종괴,강화명현.면역조화현시AE1/AE3여EMA현시양성,CK7여Vimentin현시위음성.결론재신기산세포선류적진단중,응장림상병이학여영상학、면역표형결합진행종합분석,이제고진단준학솔,방지발생오진.
Objective: To discuss the clinical basic representation, characteristics of pathology and iconography of renal oncocytoma to provide envidence in future work. Methods:Choosed data of 7 cases of renal oncocytoma from Mar. 2006 to Mar. 2012 to analyze clinical basic representation, characteristics of pathology and iconography of renal oncocytoma. Results: There were 4 cases in right and 3 cases in left, diameter 2-11 cm, 6 cases received ful nephrectomy, 1 cases simple bump resection. The tumor present circle style with clear boundary and no necrosis and hemorrhage. The tumor cels by a large number of form consistent round or polygonal cels by microscopic examination with abundant eosinophilic particles. There were 3 cases with showing low echo, echo rules, not clear boundary by B ultrasound. There were 7 cases in the renal parenchyma indicates a round mass organization, strengthen the obvious by CT. The AE1/AE3 and EMA was positive, and CK7, Vimentin was negative. Conclusion: Using pathology and iconography and immunophenotyping to diagnosis renal oncocytoma could improve diagnostic rate.