医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2012年
35期
177-178
,共2页
儿童咳嗽%变异型哮喘%孟鲁司特钠%疗效分析
兒童咳嗽%變異型哮喘%孟魯司特鈉%療效分析
인동해수%변이형효천%맹로사특납%료효분석
children cough%variant asthma%montelukast sodium%analysis of curative effect
目的探究与分析孟鲁司特钠治疗108例儿童咳嗽变异性哮喘的临床疗效.方法选取我院呼吸内科收治的儿童咳嗽变异型哮喘216例并将其作为研究对象(经本人及家长同意),按照患者意愿分为甲,乙两组,每组均为108名患者.甲组为实验组,我院采用孟鲁司特钠口服给药的治疗方案;乙组为对照组,采用抗炎平喘药糖皮质激素布地奈德的治疗方案.通过一段时间的治疗,观察并分析两组患者经不同的治疗方案治疗后的临床疗效.结果甲乙两组患者经过不同的治疗方案治疗后,甲组患者的治疗有效人数较乙组高,并且哮喘次数,气短,出汗,焦虑以及咳嗽等症状显著减少,P<0.05,具有统计学意义.结论在儿童咳嗽变异性哮喘的治疗过程中,孟鲁司特钠的治疗方案比较传统呼吸内科使用糖皮质激素的治疗方案疗效更佳显著,副作用明显减少,因此在临床上具有一定的指导意义.
目的探究與分析孟魯司特鈉治療108例兒童咳嗽變異性哮喘的臨床療效.方法選取我院呼吸內科收治的兒童咳嗽變異型哮喘216例併將其作為研究對象(經本人及傢長同意),按照患者意願分為甲,乙兩組,每組均為108名患者.甲組為實驗組,我院採用孟魯司特鈉口服給藥的治療方案;乙組為對照組,採用抗炎平喘藥糖皮質激素佈地奈德的治療方案.通過一段時間的治療,觀察併分析兩組患者經不同的治療方案治療後的臨床療效.結果甲乙兩組患者經過不同的治療方案治療後,甲組患者的治療有效人數較乙組高,併且哮喘次數,氣短,齣汗,焦慮以及咳嗽等癥狀顯著減少,P<0.05,具有統計學意義.結論在兒童咳嗽變異性哮喘的治療過程中,孟魯司特鈉的治療方案比較傳統呼吸內科使用糖皮質激素的治療方案療效更佳顯著,副作用明顯減少,因此在臨床上具有一定的指導意義.
목적탐구여분석맹로사특납치료108례인동해수변이성효천적림상료효.방법선취아원호흡내과수치적인동해수변이형효천216례병장기작위연구대상(경본인급가장동의),안조환자의원분위갑,을량조,매조균위108명환자.갑조위실험조,아원채용맹로사특납구복급약적치료방안;을조위대조조,채용항염평천약당피질격소포지내덕적치료방안.통과일단시간적치료,관찰병분석량조환자경불동적치료방안치료후적림상료효.결과갑을량조환자경과불동적치료방안치료후,갑조환자적치료유효인수교을조고,병차효천차수,기단,출한,초필이급해수등증상현저감소,P<0.05,구유통계학의의.결론재인동해수변이성효천적치료과정중,맹로사특납적치료방안비교전통호흡내과사용당피질격소적치료방안료효경가현저,부작용명현감소,인차재림상상구유일정적지도의의.
objectives:To discuss and nanalyse clinical curative effect of using montelukast sodium to treat 108 cases of children cough variant asthma.Methods:Chose 216 cases of those children cough variant asthma patients who have been admitted at respiratory medicine department of our hospital as study objectives(permitted by themselves and their parents),divided them into the first and the second group according to their wilingness,each group has 108 cases of patients.The first group was experimental group,gave oral administration of montelukast sodium as treatment to them;The second group was control group,adopted anti-inflammatory antiasthmatic glucocorticoid budesonide as treatment to them.Observed and analysed thes etwo groups’ patients’ clinical curative effects after they have been treated by different methods for a period of time. Results:After treated by different methods,the treatment effective number in the first group was more than the second group’s,and their symptoms of asthma frequencies,breathe hard, perspire,anxiety and cough were decreased significantly,p<0.05,it has statistics meaning.Conclusions:With regard to treatment for children cough variant asthma,montelukast sodium’s clinical curative effect was better than glucocorticoid’s,and its side effects diminished significantly,therefore,it has some degree of guiding value in clinical.