CAJ | 학술논문

目的了解我院药品不良反应(ADR)发生的特点和一般规律,促进临床合理用药.方法采取回顾性研究方法,对我院2011年1月~2012年8月收集上报国家药品不良反应监测网的93例 ADR 报告分别从患者性别、年龄、药品种类、给药途径、累及器官或系统及临床表现等方面进行统计、分析.结果93例 ADR 中,抗感染药物占45.2%,中药制剂占6.5%.静脉给药引发的 ADR 最多,占89.2%;以皮肤及其附件损害最多,占40.9%.结论应重视 ADR 的监测和上报工作,规范临床合理用药,保证患者用药安全.
목적료해아원약품불량반응(ADR)발생적특점화일반규률,촉진림상합리용약.방법채취회고성연구방법,대아원2011년1월~2012년8월수집상보국가약품불량반응감측망적93례 ADR 보고분별종환자성별、년령、약품충류、급약도경、루급기관혹계통급림상표현등방면진행통계、분석.결과93례 ADR 중,항감염약물점45.2%,중약제제점6.5%.정맥급약인발적 ADR 최다,점89.2%;이피부급기부건손해최다,점40.9%.결론응중시 ADR 적감측화상보공작,규범림상합리용약,보증환자용약안전.
Objective To study the characteristics and regular pattern of afverse drug reactions(ADR) occurred in our hospital so as to promote rational clinical drug use. Methods By a retrospective study, atotal of 93 ADR cases colected from January 2011 to August 2012 in our hospital were analyzed in respect of patients’age and sex,drug varieties,route of administration,organs or system involved and the clinical manifestation,etc.Results In the 93 ADR cases,45.2% were induced by antibacteria1 drugs,6.5% by the Chinese medicine. 89.2% were induced intravenously,40.9% manifested as lesions of skin and its appendants.Conclusion Importance shoud be attached to the reporting and monitoring of ADR in the clinic to standardize clinical rational drug use and ensure medication safety.