CAJ | 학술논문

目的观察酪酸梭菌活菌散与生大黄联合应用对急性重症胰腺炎胃肠功能恢复的治疗作用.方法将我科2007年1月至2011年12月期间收治的60例重症急性胰腺炎随机分为两组:对照组,予以常规持续胃肠减压、抑酸、抑制胰腺分泌、抗炎等治疗;实验组,在对照组的基础上早期予以酪酸梭菌活菌散及生大黄治疗.观察两组患者腹胀及腹痛缓解时间、肠鸣音恢复时间、肛门排气和排便恢复时间以及第1、3、5、7、9天血清中二胺氧化酶(DAO)的含量变化.结果实验组患者腹胀及腹痛缓解时间、肠鸣音恢复时间、肛门排气和排便恢复时间均明显低于对照组(P<0.01).2组患者血清DAO含量比较有统计学意义(P<0.05).结论酪酸梭菌活菌散与生大黄联合治疗能促进急性重症胰腺炎患者胃肠功能恢复.
목적관찰락산사균활균산여생대황연합응용대급성중증이선염위장공능회복적치료작용.방법장아과2007년1월지2011년12월기간수치적60례중증급성이선염수궤분위량조:대조조,여이상규지속위장감압、억산、억제이선분비、항염등치료;실험조,재대조조적기출상조기여이락산사균활균산급생대황치료.관찰량조환자복창급복통완해시간、장명음회복시간、항문배기화배편회복시간이급제1、3、5、7、9천혈청중이알양화매(DAO)적함량변화.결과실험조환자복창급복통완해시간、장명음회복시간、항문배기화배편회복시간균명현저우대조조(P<0.01).2조환자혈청DAO함량비교유통계학의의(P<0.05).결론락산사균활균산여생대황연합치료능촉진급성중증이선염환자위장공능회복.
objective: to observe the probiotics (butyric acid clostridium viable powder) and raw rhubarb combination therapy for acute severe pancreatitis gastrointestinal functional recovery treatment effect. Methods: my family in January 2007 to December 2011 were during the 60 cases of severe acute pancreatitis randomly divided into two groups: control group, to conventional continuous gastrointestinal decompression, suppression of acid, inhibit the pancreas, anti-inflammatory and so on the treatment; The experimental group, in the control group based on the early to butyric acid clostridium viable powder and raw rhubarb treatment. Observation two groups patients abdominal distension and abdominal pain relief time, bowel sound recovery time, anal exhaust and defecate recovery time and 1, 3, 5, 7, 9 days serum diamine oxidase (DAO) content changes. Results: the patients abdominal distension and abdominal pain relief time, bowel sound recovery time, anal exhaust and defecate recovery time were significantly lower than that in control group (P<0.01). Two groups patients serum DAO content is have statistical significance (P<0.05). Conclusion: probiotics and raw rhubarb combination therapy can promote for severe acute pancreatitis patients with gastrointestinal functional recovery.