CAJ | 학술논문

目的:探讨胸膜孤立性纤维瘤(solitary fibrous tumorof the pleura,SFTP)的临床特点及治疗方法.方法:回顾性分析福建医科大学附属漳州市医院胸心外科2005年12月~2012年7月年收治的10名胸膜孤立性纤维瘤患者的临床资料,10例患者均行手术切除肿瘤,术后肿瘤组织行病理检查及免疫组化分析.结果:病理检查提示肿瘤组织主要由梭形细胞和胶原纤维组成,免疫组化分析CD34、Vimentin、Bc1-2均为阳性表达,CD99部分阳性表达(2例).术后病理诊断均为胸膜孤立性纤维瘤,术后随访3个月~7年,效果良好迄今为止,未发现肿瘤转移复发.结论:手术是目前治疗SFTP的最佳方法.免疫组化对该病的诊断具有重要价值.
목적:탐토흉막고립성섬유류(solitary fibrous tumorof the pleura,SFTP)적림상특점급치료방법.방법:회고성분석복건의과대학부속장주시의원흉심외과2005년12월~2012년7월년수치적10명흉막고립성섬유류환자적림상자료,10례환자균행수술절제종류,술후종류조직행병리검사급면역조화분석.결과:병리검사제시종류조직주요유사형세포화효원섬유조성,면역조화분석CD34、Vimentin、Bc1-2균위양성표체,CD99부분양성표체(2례).술후병리진단균위흉막고립성섬유류,술후수방3개월~7년,효과량호흘금위지,미발현종류전이복발.결론:수술시목전치료SFTP적최가방법.면역조화대해병적진단구유중요개치.
Objective:to solitary fibrous tumor of the pleura (solitary fibrous tumorof the pleura, SFTP) of the clinical features and treatment methods.Methods:a retrospective analysis of Zhangzhou Hospital affiliated to Fujian Medical University cardiothoracic surgery from December to 2012 2005 July years were 10 solitary fibrous tumor of the pleura in patients with clinical data,10 cases underwent operation resection of the tumor, postoperative tumor tissue for pathological examination and immunohistochemical analysis.Results:of histologic examination of tumor tissue is mainly composed of spindle cels and colagen fiber composition, immunohistochemical analysis of CD34, Vimentin, Bc1-2 are positive, the positive expression of CD99 part (2 cases). The postoperative pathological diagnosis for solitary fibrous tumor of the pleura, postoperative folow up of 3 months ~7 years, effect is good so far, revealed no tumor recurrence and metastasis. Conclusion operation is the best method of treatment of SFTP. Immunohistochemistry in the diagnosis of this disease is of important value.