药品评价
藥品評價
약품평개
DRUG REEVALUATION
2013年
4期
19-21
,共3页
蒙药%阿那日%提取部位
矇藥%阿那日%提取部位
몽약%아나일%제취부위
Mongolian Medicine%Anari%Extract Part
目的:研究阿那日八味散不同提取部位的主要药理作用.方法:采用胃排空、小肠推进、幽门结扎型胃溃疡试验模型,研究阿那日八味散不同提取部位的药理作用.结果:阿那日八味散挥发油部位、醇提物部位、水提物部位都具有促进胃排空,促进小肠推进,抑制胃溃疡形成的作用;阿那日八味散醇提物部分、水提物部位能够抑制大鼠胃液分泌,降低胃液游离酸度和总酸度,其中可以显著降低胃酸中游离酸的量.结论:阿那日八味散各提取部位均有改善胃肠道疾病相关症状的作用,在进行剂型改革时各提取部位均应保留.
目的:研究阿那日八味散不同提取部位的主要藥理作用.方法:採用胃排空、小腸推進、幽門結扎型胃潰瘍試驗模型,研究阿那日八味散不同提取部位的藥理作用.結果:阿那日八味散揮髮油部位、醇提物部位、水提物部位都具有促進胃排空,促進小腸推進,抑製胃潰瘍形成的作用;阿那日八味散醇提物部分、水提物部位能夠抑製大鼠胃液分泌,降低胃液遊離痠度和總痠度,其中可以顯著降低胃痠中遊離痠的量.結論:阿那日八味散各提取部位均有改善胃腸道疾病相關癥狀的作用,在進行劑型改革時各提取部位均應保留.
목적:연구아나일팔미산불동제취부위적주요약리작용.방법:채용위배공、소장추진、유문결찰형위궤양시험모형,연구아나일팔미산불동제취부위적약리작용.결과:아나일팔미산휘발유부위、순제물부위、수제물부위도구유촉진위배공,촉진소장추진,억제위궤양형성적작용;아나일팔미산순제물부분、수제물부위능구억제대서위액분비,강저위액유리산도화총산도,기중가이현저강저위산중유리산적량.결론:아나일팔미산각제취부위균유개선위장도질병상관증상적작용,재진행제형개혁시각제취부위균응보류.
Objective: To study the main pharmacological effects of different extract parts of Mongolian medicine Anari Bawei powder. Methods: with the animal models of the gastric emptying, intestinal propulsion and gastric ulcer induced by pyloric ligation, the main pharmacological effects of different extract parts of Mongolian medicine Anari Bawei powder were studied .Results: the volatile oil part , the alcohol extract part and the water extract part of Anari Bawei powder could promote gastric emptying, promote intestinal propulsion and inhibit gastric ulcer formation; the alcohol extract part and the water extract part could inhibit rat gastric juice secretion, reduce gastric juice free acidity and total acidity, especially the amount of free acid in the acid. Conclusion: All the three extract parts of Mongolian medicine Anari Bawei powder are the active ingredients and should be retained when changing the pharmaceutical dosage form.
