CAJ | 학술논문

前列腺癌是欧美国家最常见的男性泌尿生殖系统恶性肿瘤.近年来,我国前列腺癌的发病率明显升高.肿瘤转移是导致多数前列腺癌患者治疗失败的重要原因,而肿瘤细胞进入外周血循环系统是远处器官转移的先决条件.外周血中循环肿瘤细胞(circulating tumor cell,CTC)因能反映患者个体的肿瘤特征,且较易获得而受到众多学者的关注.本文就CTC的检测方法以及CTC计数和分子标志物在前列腺癌中的研究进展作一综述.
전렬선암시구미국가최상견적남성비뇨생식계통악성종류.근년래,아국전렬선암적발병솔명현승고.종류전이시도치다수전렬선암환자치료실패적중요원인,이종류세포진입외주혈순배계통시원처기관전이적선결조건.외주혈중순배종류세포(circulating tumor cell,CTC)인능반영환자개체적종류특정,차교역획득이수도음다학자적관주.본문취CTC적검측방법이급CTC계수화분자표지물재전렬선암중적연구진전작일종술.
Prostate cancer is the most common urogenital malignant tumor among males in Western countries. Recently, more and more prostate cancer patients were diagnosed in China. Tumor metastasis is one of the main cause for the failure of prostate cancer treatment. Tumor cells entering into circulation system is the prerequisite for tumor metastasis in the distant organs. Many studies began to focus on circulating tumor cells in peripheral blood (CTC) because it could represent individual tumor characteristics. This review focused on the detection, enumeration and biomarkers of CTC.