CAJ | 학술논문

以生物检测与分子诊断技术发展为背景,总结了团队在医学诊断、疾控、食品安全、检疫检验、生物学医学科学研究等领域的分子诊断高端装备的研制情况,重点介绍了实时荧光定量聚合酶链式反应(PCR)分子诊断仪关键技术的研发及仪器工程化技术、检测性能的验证和在社会发展重点领域中的成功应用,手持式腺嘌呤核苷三磷酸(ATP)生物发光法细菌快速检测仪的研发与应用,以及后续的全自动核酸定量检测与高分辨分析设备研制.
이생물검측여분자진단기술발전위배경,총결료단대재의학진단、질공、식품안전、검역검험、생물학의학과학연구등영역적분자진단고단장비적연제정황,중점개소료실시형광정량취합매련식반응(PCR)분자진단의관건기술적연발급의기공정화기술、검측성능적험증화재사회발전중점영역중적성공응용,수지식선표령핵감삼린산(ATP)생물발광법세균쾌속검측의적연발여응용,이급후속적전자동핵산정량검측여고분변분석설비연제.
Based on biological detection and molecular diagnostics technology development,the author summarized high-end equipment independent research in medical diagnostics,disease control,food safety,quar-antine inspection,biology and medical research field of molecular diagnostics. The paper focused on research and development of key technology and instrumentation engineering technology,detection performance verifica-tion and successful application in the field of social development priorities of the real-time fluorescence quantita-tive polymerase chain reaction(PCR)nucleic acid detector,diagnosis of high-end equipment,the development and application and subsequent automatic nucleic acid directional monitoring with high-resolution analysis equip-ment development of handheld adenosine triphosphate(ATP)bioluminescence rapid detection of bacteria.