CAJ | 학술논문

目的探讨可即邦医用胶原蛋白海绵(collagen sponge,CS)在控制全膝关节置换术后出血中的应用价值.方法选取2011年6月至2012年6月,142例患者,男37例,女105例,平均年龄68.7岁.随机分为两组,常规进行膝关节置换,CS 组71例,术中使用可即邦医用胶原蛋白海绵,另71例术中未予使用,作为对照组.对每个患者我们均记录术后可见失血量、术中失血量、总失血量、术前术后血红蛋白值、两组中的输血患者数,以及并发症等.结果 CS 组术后可见失血量为(195.3±37.0) ml,对照组(279.2±40.1) ml,两组差异有统计学意义(P=0.047).CS 组和对照组患者术后24 h 血红蛋白下降值分别为(30.3±3.4) g/L、(39.2±4.7) g/L,差异有统计学意义(P<0.01).CS 组和对照组分别有10例和21例患者输血,术后输血人数差异有统计学意义(P=0.025).两组中各有1例患者发生深静脉血栓;CS 组术后发生1例切口表浅部位感染,1例切口表浅皮肤坏死,对照组有1例切口表浅部位感染.差异均无统计学意义.结论可即邦医用胶原蛋白海绵可以有效降低 TKA 的术后失血量.
목적탐토가즉방의용효원단백해면(collagen sponge,CS)재공제전슬관절치환술후출혈중적응용개치.방법선취2011년6월지2012년6월,142례환자,남37례,녀105례,평균년령68.7세.수궤분위량조,상규진행슬관절치환,CS 조71례,술중사용가즉방의용효원단백해면,령71례술중미여사용,작위대조조.대매개환자아문균기록술후가견실혈량、술중실혈량、총실혈량、술전술후혈홍단백치、량조중적수혈환자수,이급병발증등.결과 CS 조술후가견실혈량위(195.3±37.0) ml,대조조(279.2±40.1) ml,량조차이유통계학의의(P=0.047).CS 조화대조조환자술후24 h 혈홍단백하강치분별위(30.3±3.4) g/L、(39.2±4.7) g/L,차이유통계학의의(P<0.01).CS 조화대조조분별유10례화21례환자수혈,술후수혈인수차이유통계학의의(P=0.025).량조중각유1례환자발생심정맥혈전;CS 조술후발생1례절구표천부위감염,1례절구표천피부배사,대조조유1례절구표천부위감염.차이균무통계학의의.결론가즉방의용효원단백해면가이유효강저 TKA 적술후실혈량.
Objective To investigate the effects of Kejibang medical collagen sponge (CS) in controlling post-operative bleeding following total knee replacement surgery. Methods From June 2011 to June 2012, 142 patients (37 males and 105 females, mean age 68.7 years) were randomly divided into 2 groups prior to conventional knee replacements. CS group: 71 cases using medical collagen sponge during the surgery. Control group: 71 cases without the use of CS during the surgery. Each patient was monitored and recorded for visible blood loss, intra-operative blood loss, total blood loss, pre-operative and post-operative hemoglobin values, the amounts of patients accepting blood transfusion in 2 groups, as well as any complications. Results The CS group visible blood loss after the surgery was (195.3±37.0) ml. Compared with (279.2±40.1) ml of the control group, the differences were statistically significant (P=0.047). 24-hour hemoglobin drop level in CS group and control group patients were (30.3±3.4) g/L and (39.2±4.7) g/L, respectively. The differences were statistically significant (P<0.01). CS group and the control group contained 10 cases and 21 cases respectively requiring post-operative blood transfusion. The differences were statistically significant (P=0.025). During postoperative care, there was 1 patient with deep venous thrombosis in each group. In CS group there was 1 case of superficial incision site infection, and 1 case of superficial incision site skin necrosis. The control group contained 1 case of superficial incision site infection. The differences were not statistically significant. Conclusions The use of Kejibangmedical collagen sponge can effectively reduce total knee arthroplasty post-operative blood loss.