CAJ | 학술논문

目的研究前列腺穿刺活检对前列腺癌根治术后尖部病理结果的预测价值;方法收集2001年1月至2012年7月在本院泌尿外科行前列腺穿刺并行前列腺癌根治术的标本147对,采用四格表法比较穿刺时及根治术后前列腺尖部病理结果;结果穿刺时尖部阳性者共79例,根治术后尖部阳性者共31例,其中切缘阳性9例,占穿刺尖部阳性者11.3%.穿刺时及根治术后尖部均阳性22例,灵敏度70.9%,穿刺时及根治术后尖部均阴性59例,特异度50.8%,穿刺尖部结果和术后病理一致99对,一致率55.1%,穿刺尖部阴性但术后尖部阳性仅 9对,假阴性率29.0%,穿刺尖部阳性但术后尖部阴性的57对,假阳性率49.1%;结论前列腺穿刺活检尖部阳性率高并不能预示根治术后尖部切缘阳性率高,加强术前风险评估、术中合理处理前列腺尖部、采取有效措施可以降低尖部切缘阳性率.
목적연구전렬선천자활검대전렬선암근치술후첨부병리결과적예측개치;방법수집2001년1월지2012년7월재본원비뇨외과행전렬선천자병행전렬선암근치술적표본147대,채용사격표법비교천자시급근치술후전렬선첨부병리결과;결과천자시첨부양성자공79례,근치술후첨부양성자공31례,기중절연양성9례,점천자첨부양성자11.3%.천자시급근치술후첨부균양성22례,령민도70.9%,천자시급근치술후첨부균음성59례,특이도50.8%,천자첨부결과화술후병리일치99대,일치솔55.1%,천자첨부음성단술후첨부양성부 9대,가음성솔29.0%,천자첨부양성단술후첨부음성적57대,가양성솔49.1%;결론전렬선천자활검첨부양성솔고병불능예시근치술후첨부절연양성솔고,가강술전풍험평고、술중합리처리전렬선첨부、채취유효조시가이강저첨부절연양성솔.
Objective To evaluate the value of prostate biopsy in predicting pathology results of prostate apex after radical surgery; Methods A retrospective study on pathology results of prostate apex in 147 prostate cancer patients, who received needle biopsy (NB) test and radical prostatectomy(RP) treatment in our hospital from January 2001 to July 2012 was carried out.The pathological results of prostate apex from needle biopsy(NB) test and radical prostatectomy(RP) were compared. Results Total of 79 positive cases were found in NB test, 31 positive cases after RP, including 9 apex margin positive cases, which accounting for 11.3% of NB apex positive cases. Twenty-two cases were double positive in these two methods, the test sensitivity was 70.9%, 59 cases were double negative, the specificity was 50.8%. The pathological results of 99 cases in NB test were consistent with that of RP, the consistency rate was 55.1%, 9 cases were NB negative but RP positive, the false negative rate was 29.0%, and 57 cases were NB positive but RP negative, the false positive rate was 49.1%; Conclusion The high apex positive rate of Prostate biopsy did not mean high positive rate of prostate apex margin after radical surgery. Careful preoperative risk assessment and proper prostate apex handling during operation will be helpful for decrease the positive of margin rate.