CAJ | 학술논문

目的观察联合应用布地奈德鼻喷剂和地氯雷他定片治疗过敏性鼻炎的临床疗效和安全性.方法?将该院门诊2010年3月—2012年3月诊断为过敏性鼻炎的患者126例随机分为3组,观察组42例,给予布地奈德鼻喷剂联合地氯雷他定片治疗,对照A组42例,单用布地奈德鼻喷剂治疗,对照B组42例,单用地氯雷他定片治疗.疗程2周,记录3组治疗前后的症状评分并进行比较.结果观察组总有效率为92.8%,明显优于对照A组的73.8%和对照B组的66.7%(P<0.05),且三者不良反应发生率差异无统计学意义(P>0.05).结论?联合应用布地奈德鼻喷剂和地氯雷他定片治疗过敏性鼻炎疗效优于单用一种药物,且没有明显不良反应,值得临床推广使用.
목적관찰연합응용포지내덕비분제화지록뢰타정편치료과민성비염적림상료효화안전성.방법?장해원문진2010년3월—2012년3월진단위과민성비염적환자126례수궤분위3조,관찰조42례,급여포지내덕비분제연합지록뢰타정편치료,대조A조42례,단용포지내덕비분제치료,대조B조42례,단용지록뢰타정편치료.료정2주,기록3조치료전후적증상평분병진행비교.결과관찰조총유효솔위92.8%,명현우우대조A조적73.8%화대조B조적66.7%(P<0.05),차삼자불량반응발생솔차이무통계학의의(P>0.05).결론?연합응용포지내덕비분제화지록뢰타정편치료과민성비염료효우우단용일충약물,차몰유명현불량반응,치득림상추엄사용.
Objective To observe the clinical efficacy and safety of allergic rhinitis with combination of budesonide nasal spray and Loratadine tablets. Method 126 cases of allergic rhinitis patients in our clinic from March 2010 to March 2012 were given randomly divided into three groups,42 patients of the observation group,were given budesonide nasal spray jointly loratadine tablets in the treatment. 42 patients of control A group,were simply given budesonide nasal spray,42 cases of control group B were simply given desloratadine tablets in the treatment. Symptom scores of the three groups were record and compared two weeks’s later before and after treatment. Results The total effective rate was 92.8% in the observation group,significantly better than the control group A 73.8%and the and control group B 66.7%(P <0.05),and the three incidence of adverse reactions were not significant different(P >0.05). Conclusion The combination of budesonide nasal spray and Desloratadine tablets on allergic rhinitis is more effective than the single drug,and there is no significant adverse reactions,is worthy of clinical use.