CAJ | 학술논문

目的:研制适用于临床的不粘伤口的、无油腻感的、可以提供湿性愈合环境的纱布.方法润湿性凡士林纱布是将添加了水凝胶颗粒和医用高分子材料凝固剂的凡士林涂布于聚酯纤维网上.考察了水凝胶颗粒和医用高分子材料凝固剂对凡士林性能的影响,并研究了凡士林纱布的涂布或浸渍工艺.对凡士林纱布的皮肤刺激性、致敏反应和细胞毒性进行了试验.结果润湿性凡士林纱布的含胶量为122g/m2,润湿性凡士林纱布油胶的断裂伸长率为169%,回缩率为47%,润湿性凡士林纱布涂布成半封闭状且上胶均匀;无皮肤刺激性、无致敏反应及无细胞毒性.结论该润湿性凡士林纱布制备工艺切实可行,稳定可靠,为临床使用提供了依据.
목적:연제괄용우림상적불점상구적、무유니감적、가이제공습성유합배경적사포.방법윤습성범사림사포시장첨가료수응효과립화의용고분자재료응고제적범사림도포우취지섬유망상.고찰료수응효과립화의용고분자재료응고제대범사림성능적영향,병연구료범사림사포적도포혹침지공예.대범사림사포적피부자격성、치민반응화세포독성진행료시험.결과윤습성범사림사포적함효량위122g/m2,윤습성범사림사포유효적단렬신장솔위169%,회축솔위47%,윤습성범사림사포도포성반봉폐상차상효균균;무피부자격성、무치민반응급무세포독성.결론해윤습성범사림사포제비공예절실가행,은정가고,위림상사용제공료의거.
Objective: The purpose is to research a kind of novel clinical gauze, which has non-stick wound and no greasy feeling and can provide the wet healing environment. Methods: the Wettability Vaseline gauze was fabricated by coating vaseline added hydrogel partical and biopolymer coagulant on polyester fiber network . The effect of hydrogel partical and biopolymer coagulant on the properties of vaseline, and the coating or dipping preparation of the vaseline gauze were researched. The skin irritation, anaphylactic reactions, and cytotoxicity of the vaseline gauze were tested. Results: The gel content of the Wet ability Vaseline gauze is 122 g/m2. The elongation at break of the gauze is 169% and the retraction rate is 47%. The vaseline was coated on the gauze into semi-closed shape and evenly distributed. The novel gauze has non skin irritation, non anaphylactic reaction, and non cytotoxicity. Conclusion: The preparation of the Wet ability Vaseline gauze is practicable and it provides a basis for clinical use.