CAJ | 학술논문

目的探讨影响胰腺癌患者长期生存的预后因素.方法对本院2001年10月-2011年1月资料完整的551例胰腺癌患者进行回顾性研究,进行单因素生存分析.结果研究显示,性别、年龄、是否存在肝转移、是否手术、是否进行放化疗与胰腺癌患者的长期生存相关,而肿瘤部位、吸烟、饮酒及是否病理确诊与胰腺癌患者的生存时间无关.Cox多因素分析同样显示,年龄、是否存在肝转移、是否手术、是否进行放化疗等4个指标也是胰腺癌患者能否获得长期生存的独立预后因素.结论年龄、是否手术、是否进行放化疗与胰腺癌患者的生存相关,可作为胰腺癌患者的独立预后因素.早期发现、早期治疗和进行手术治疗为主辅以放化疗的综合治疗模式,是提高胰腺癌患者生存率的关键.
목적탐토영향이선암환자장기생존적예후인소.방법대본원2001년10월-2011년1월자료완정적551례이선암환자진행회고성연구,진행단인소생존분석.결과연구현시,성별、년령、시부존재간전이、시부수술、시부진행방화료여이선암환자적장기생존상관,이종류부위、흡연、음주급시부병리학진여이선암환자적생존시간무관.Cox다인소분석동양현시,년령、시부존재간전이、시부수술、시부진행방화료등4개지표야시이선암환자능부획득장기생존적독립예후인소.결론년령、시부수술、시부진행방화료여이선암환자적생존상관,가작위이선암환자적독립예후인소.조기발현、조기치료화진행수술치료위주보이방화료적종합치료모식,시제고이선암환자생존솔적관건.
Objective To investigate the prognostic factors that affect the long-term survival of patients with pancreatic cancer. Methods 551 pancreatic cancer patients from October 2001 to January 2011 with complete data were retrospectively analyzed by univariate survival analysis. Results The study showed that gender, age, liver metastases, surgery, radiotherapy and chemotherapy in patients with pancreatic cancer related to long-term survival. However, the site of tumor, smoking, alcohol consumption and pathology diagnosis is not correlated with survival. Cox multivariate analysis also showed that age, liver metastases, surgery, chemoradiotherapy are independent prognostic factor for pancreatic cancer patients. Conclusion Age, surgery, chemotherapy are independent prognostic factors for pancreatic cancer patients. Early detection, early treatment and surgery-based integrated treatment model supplemented by radiotherapy and chemotherapy is the key to improve the survival rate of pancreatic cancer patients.