CAJ | 학술논문

目的:在重症手足口病救治中,探讨一种降低神经源性肺水肿、肺出血的有效方法.方法:将64例重症手足口病患儿分为治疗组及对照组,两组均常规应用降低颅内压、人血静脉丙种球蛋白、糖皮质激素、抗病毒、抗感染对症处理等,治疗组在入院时即给予呋塞米1 mg/kg 静脉注射.结果:治疗组能明显缩短中枢神经系统症状改善时间,减少神经源性肺水肿的发生率,与对照组比较差异有统计学意义(P<0.05).结论:早期应用呋塞米能明显缩短重症手足口病患儿中枢神经系统改善时间,减少神经源性肺水肿、肺出血的发生率.
목적:재중증수족구병구치중,탐토일충강저신경원성폐수종、폐출혈적유효방법.방법:장64례중증수족구병환인분위치료조급대조조,량조균상규응용강저로내압、인혈정맥병충구단백、당피질격소、항병독、항감염대증처리등,치료조재입원시즉급여부새미1 mg/kg 정맥주사.결과:치료조능명현축단중추신경계통증상개선시간,감소신경원성폐수종적발생솔,여대조조비교차이유통계학의의(P<0.05).결론:조기응용부새미능명현축단중증수족구병환인중추신경계통개선시간,감소신경원성폐수종、폐출혈적발생솔.
Objective:To explore an effective method to reduce neurogenic pulmonary edema,and pneumorrhagia in the treatment of severe hand,foot and mouth disease.Method:A retrospective analysis was used in 64 cases of severe hand,foot and mouth disease that were divided into treatment group and control group,both of which normally applied intracranial step-down,intravenous gamma globulin,corticosteroids,anti-virus,and anti-infection symptomatic treatment and so on.Treatment group,however,were given 1 mg/kg of Furosemide intravenous injections at the time of admission.Result:The time of the improvement in central nervous system symptoms of treatment group was significantly shortened,and the occurrence rates of the neurogenic pulmonary edema and pneumorrhagia was reduced-an apparent difference compared with the control group(P<0.05). Conclusion:Early application of Furosemide can significantly shorten the time of improvement in the central nervous system symptoms of severe HFMD patients and reduce the occurrence of neurogenic pulmonary edema and pneumorrhagia.