中国医学影像学杂志
中國醫學影像學雜誌
중국의학영상학잡지
CHINESE JOURNAL OF MEDICAL IMAGING
2012年
12期
948-952
,共5页
颅内动脉瘤%体层摄影术,螺旋计算机%脑血管造影术%Meta 分析
顱內動脈瘤%體層攝影術,螺鏇計算機%腦血管造影術%Meta 分析
로내동맥류%체층섭영술,라선계산궤%뇌혈관조영술%Meta 분석
Intracranial aneurysm%Tomography, spiral computed%Cerebral angiography%Meta-analysis
目的对多层螺旋 CT 血管造影(CTA)诊断颅内动脉瘤的文献进行荟萃分析,评价多层螺旋 CTA 对颅内动脉瘤的诊断价值.资料与方法以多层螺旋 CT、CT 血管造影、数字血管减影血管造影、颅内动脉瘤为检索词,检索 PubMed、EBSCO、Springer、中国知网(CNKI)以及 Cochrane 图书馆数据库,文献检索时间2005-01~2011-01,同时检索纳入文献的参考文献.纳入探讨以数字减影血管造影(DSA)为“金标准”的关于 CTA 诊断颅内动脉瘤的文献,进行质量评价和资料提取,检验研究间的异质性,对诊断准确度指标进行 Meta 分析,绘制森林图,并进行综合受试者工作特征曲线(SROC)分析.结果符合纳入标准的文献共25篇,各研究之间存在低度异质性,按照随机效应模型计算汇总敏感度、特异度与诊断优势比分别为0.96(95% CI :0.95~0.97)、1.00(95% CI :1.00~1.00);SROC 下面积为0.9988,Q 指数为0.9894.结论多层螺旋 CTA 诊断颅内动脉瘤具有较高的敏感度及特异度,与 DSA 诊断价值相当,在颅内动脉瘤的筛查与诊断中具有重要临床意义.
目的對多層螺鏇 CT 血管造影(CTA)診斷顱內動脈瘤的文獻進行薈萃分析,評價多層螺鏇 CTA 對顱內動脈瘤的診斷價值.資料與方法以多層螺鏇 CT、CT 血管造影、數字血管減影血管造影、顱內動脈瘤為檢索詞,檢索 PubMed、EBSCO、Springer、中國知網(CNKI)以及 Cochrane 圖書館數據庫,文獻檢索時間2005-01~2011-01,同時檢索納入文獻的參攷文獻.納入探討以數字減影血管造影(DSA)為“金標準”的關于 CTA 診斷顱內動脈瘤的文獻,進行質量評價和資料提取,檢驗研究間的異質性,對診斷準確度指標進行 Meta 分析,繪製森林圖,併進行綜閤受試者工作特徵麯線(SROC)分析.結果符閤納入標準的文獻共25篇,各研究之間存在低度異質性,按照隨機效應模型計算彙總敏感度、特異度與診斷優勢比分彆為0.96(95% CI :0.95~0.97)、1.00(95% CI :1.00~1.00);SROC 下麵積為0.9988,Q 指數為0.9894.結論多層螺鏇 CTA 診斷顱內動脈瘤具有較高的敏感度及特異度,與 DSA 診斷價值相噹,在顱內動脈瘤的篩查與診斷中具有重要臨床意義.
목적대다층라선 CT 혈관조영(CTA)진단로내동맥류적문헌진행회췌분석,평개다층라선 CTA 대로내동맥류적진단개치.자료여방법이다층라선 CT、CT 혈관조영、수자혈관감영혈관조영、로내동맥류위검색사,검색 PubMed、EBSCO、Springer、중국지망(CNKI)이급 Cochrane 도서관수거고,문헌검색시간2005-01~2011-01,동시검색납입문헌적삼고문헌.납입탐토이수자감영혈관조영(DSA)위“금표준”적관우 CTA 진단로내동맥류적문헌,진행질량평개화자료제취,검험연구간적이질성,대진단준학도지표진행 Meta 분석,회제삼림도,병진행종합수시자공작특정곡선(SROC)분석.결과부합납입표준적문헌공25편,각연구지간존재저도이질성,안조수궤효응모형계산회총민감도、특이도여진단우세비분별위0.96(95% CI :0.95~0.97)、1.00(95% CI :1.00~1.00);SROC 하면적위0.9988,Q 지수위0.9894.결론다층라선 CTA 진단로내동맥류구유교고적민감도급특이도,여 DSA 진단개치상당,재로내동맥류적사사여진단중구유중요림상의의.
Purpose To evaluate the diagnostic value of multi-slice spiral CTA in intracranial aneurysms through meta-analysis of relevant literature. Materials and Methods Studies were located through electronic searching of the PubMed, EBSCO, Springer, CNKI, Cochrane library (from January 2005 to January 2011), the key words: multi-slice spiral computer, multi-row spiral computer, computed angiography, intracranial aneurysm, digital subtraction angiography. Bibliographies of the retrieved articles were also checked. All the studies concerning the diagnosis of intracranial aneurysm using CTA were searched and reviewed. Studies with DSA as the gold standard were adopted as eligible. Subsequently, the characteristics of the included articles were appraised and extracted. Data on accuracy of included studies were extracted for further heterogeneity exploring, statistical pooling and SROC were analyzed. Results Totally 25 studies met the inclusion criteria. The heterogeneity was found in these studies. The pooled accuracy indicators like sensitivity, specificity were 0.96 (95% CI: 0.95-0.97), 1.00 (95% CI: 1.00-1.00), respectively; the area under of SROC curve was 0.9988 and the Q index was 0.9894. Conclusion Multi-slice spiral CTA has high sensitivity and specificity for diagnosing intracranial aneurysms and has considerable value with the DSA. It has important clinical value in screening and diagnosing intracranial aneurysms.
