CAJ | 학술논문

目的观察成人腰椎侧凸患者椎体骨小梁的改变及其与骨质疏松的相关性.资料与方法收集经腰椎 CT 检查确诊的腰椎侧凸患者(病例组)及无腰椎侧凸的腰腿痛患者(对照组)各100例,分别测量两组受试者椎体 CT 值及椎体骨小梁容积百分比(BV/TV);同时重建骨小梁的三维图像,观察骨小梁的结构改变.结果病例组椎体 CT 值及 BV/TV 值均较对照组明显降低(P<0.05).容积再现三维图像显示,病例组患者骨小梁连续性中断,数目减少;对照组患者骨小梁相对致密.所有受试者 BV/TV 值与年龄呈负相关(r=―0.513, P<0.01).结论随着年龄增加, BV/TV 值降低,骨松质发生改变,腰椎侧凸发生率提高.骨小梁结构稀疏、数目减少及骨松质发生改变是成人发生腰椎侧凸的主要因素.
목적관찰성인요추측철환자추체골소량적개변급기여골질소송적상관성.자료여방법수집경요추 CT 검사학진적요추측철환자(병례조)급무요추측철적요퇴통환자(대조조)각100례,분별측량량조수시자추체 CT 치급추체골소량용적백분비(BV/TV);동시중건골소량적삼유도상,관찰골소량적결구개변.결과병례조추체 CT 치급 BV/TV 치균교대조조명현강저(P<0.05).용적재현삼유도상현시,병례조환자골소량련속성중단,수목감소;대조조환자골소량상대치밀.소유수시자 BV/TV 치여년령정부상관(r=―0.513, P<0.01).결론수착년령증가, BV/TV 치강저,골송질발생개변,요추측철발생솔제고.골소량결구희소、수목감소급골송질발생개변시성인발생요추측철적주요인소.
Purpose To study the correlation between vertebral osteoporosis and trabecular bone change in adult patients with lumbar scoliosis. Materials and Methods One hundred patients with lumbar scoliosis diagnosed by using CT (patient group) and one hundred patients with a history of backleg pain but not diagnosed as lumbar scoliosis (control group) were enrolled. The CT readings of vertebra and vertebral trabecular bone volume to tissue volume (BV/TV) of patients in both groups were measured. Three-dimensional reconstruction of trabecular bone was performed to visualize its structure change. Results The measured CT and BV/TV values in patient group were significantly higher than those in control group (P<0.05). Three-dimensional volume rendering showed patient group had detectable trabecular discontinuities, reduced trabecular bone number, and less dense trabecular. There was a significant negative correlation between BV/TV and age (r=―0.513, P<0.01) for all the participants. Conclusion As a consequence of aging, the BV/TV value is reduced, the structure of spongy bone is changed and consequently, the incidence rate of vertebral osteoporosis is increased. The sparse trabecular structure, reduced trabecular number, and the structure change in spongy bone are the main reasons for adult lumbar scoliosis.