中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2012年
12期
2137-2138
,共2页
重症肺炎%小儿%酚妥拉明%盐酸氨溴索
重癥肺炎%小兒%酚妥拉明%鹽痠氨溴索
중증폐염%소인%분타랍명%염산안추색
Svere mycoplasma pneumonia%Children%Phentolamine%Ambroxol hydrochloride
目的:探讨酚妥拉明联合盐酸氨溴索治疗小儿重症肺炎的临床疗效.方法:选择2010年1月~2012年4月本院儿科收治的重症肺炎患儿94例,按照随机数字表法分为观察组和对照组,每组各47例.两组患儿均接受常规对症和抗感染治疗,观察组在此基础上静脉滴注酚妥拉明5μg/(kg·min),每次1h,每日2次,同时给予盐酸氨溴索7.5~15mg/次,每日2次,7d为1个疗程.并对两组患儿咳嗽、哮鸣音、湿啰音等临床症状消失时间,以及临床疗效进行比较.结果:观察组患儿治疗总有效率达93.6%,显著高于对照组,且观察组住院时间仅为(9.8±3.0)d,退热、心衰纠正和各项临床症状改善时间均显著低于观察组(P<0.05).结论:酚妥拉明联合盐酸氨溴索能够显著降低缩短临床症状及体征消失时间,且大大提高临床疗效,值得临床推广.
目的:探討酚妥拉明聯閤鹽痠氨溴索治療小兒重癥肺炎的臨床療效.方法:選擇2010年1月~2012年4月本院兒科收治的重癥肺炎患兒94例,按照隨機數字錶法分為觀察組和對照組,每組各47例.兩組患兒均接受常規對癥和抗感染治療,觀察組在此基礎上靜脈滴註酚妥拉明5μg/(kg·min),每次1h,每日2次,同時給予鹽痠氨溴索7.5~15mg/次,每日2次,7d為1箇療程.併對兩組患兒咳嗽、哮鳴音、濕啰音等臨床癥狀消失時間,以及臨床療效進行比較.結果:觀察組患兒治療總有效率達93.6%,顯著高于對照組,且觀察組住院時間僅為(9.8±3.0)d,退熱、心衰糾正和各項臨床癥狀改善時間均顯著低于觀察組(P<0.05).結論:酚妥拉明聯閤鹽痠氨溴索能夠顯著降低縮短臨床癥狀及體徵消失時間,且大大提高臨床療效,值得臨床推廣.
목적:탐토분타랍명연합염산안추색치료소인중증폐염적림상료효.방법:선택2010년1월~2012년4월본원인과수치적중증폐염환인94례,안조수궤수자표법분위관찰조화대조조,매조각47례.량조환인균접수상규대증화항감염치료,관찰조재차기출상정맥적주분타랍명5μg/(kg·min),매차1h,매일2차,동시급여염산안추색7.5~15mg/차,매일2차,7d위1개료정.병대량조환인해수、효명음、습라음등림상증상소실시간,이급림상료효진행비교.결과:관찰조환인치료총유효솔체93.6%,현저고우대조조,차관찰조주원시간부위(9.8±3.0)d,퇴열、심쇠규정화각항림상증상개선시간균현저저우관찰조(P<0.05).결론:분타랍명연합염산안추색능구현저강저축단림상증상급체정소실시간,차대대제고림상료효,치득림상추엄.
Objective:To investigate the clinical effect of phentolamine combined with ambroxol hydrochloride in treating svere mycoplasma pneumonia in children. Methods:94 children with svere mycoplasma pneumonia were selected and divided into two groups randomly and for each 47. All the children were given common symptomatic and anti-infection treatment, and children in observation group were given phentolamine 5μg/(kg·min) by intravenous infusion, each time for 1h and twice per day, combined with ambroxol hydrochloride with dose of 7.5-15mg per time and twice per day, 7 days for a course.Results:The hospital time and total efficiency of observation group was 9.8±3.0d and 93.6%, and all the time of clinical improvement were significantly better than that of control group (P<0.05).Conclusion:Phentolamine combined with ambroxol hydrochloride in treating svere mycoplasma pneumonia in children has a good efficiency and significantly lower the time of symptoms and signs disappeared, and deserve to clinical.
