中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
1期
37-38
,共2页
多囊卵巢综合症%非酒精性脂肪肝%危险因素
多囊卵巢綜閤癥%非酒精性脂肪肝%危險因素
다낭란소종합증%비주정성지방간%위험인소
Polycystic ovary syndrome%Non-alcoholic fatty liver%Risk factors
目的:调查多囊卵巢综合征(PCOS)中非酒精性脂肪肝(NAFLD)的发病情况并对相关危险因素做出分析.方法:将本院2001年2月~2010年3月收治的142例PCOS患者按照B超诊断分为两组,非NAFLD组92例,NAFLD组50例,比较两组之间BMI、To、FINS、2hINS、Homa-IR、CHO、ALT、AST等生化、代谢指标.结果:142例PCOS 患者经B超诊断,NAFLD的发生率为36.62%(52/142);PCOS 患者中已婚患者的NAFLD发病率(37.50%)与未婚患者的NAFLD发病率(33.33%)之间差异无统计学意义(P>0.05);肥胖PCOS 患者中NAFLD的发病率(66.07%)明显高于非肥胖NAFLD的发病率(17.44%),且差异有统计学意义(P<0.05);NAFLD组上述各项生化、代谢指标均大于非NAFLD组,且差异均有统计学意义(P<0.05).结论:控制体重、适量运动、低脂饮食、改善胰岛素抵抗、早期检测和干预是防止PCOS 患者中NAFLD发生的重要措施.
目的:調查多囊卵巢綜閤徵(PCOS)中非酒精性脂肪肝(NAFLD)的髮病情況併對相關危險因素做齣分析.方法:將本院2001年2月~2010年3月收治的142例PCOS患者按照B超診斷分為兩組,非NAFLD組92例,NAFLD組50例,比較兩組之間BMI、To、FINS、2hINS、Homa-IR、CHO、ALT、AST等生化、代謝指標.結果:142例PCOS 患者經B超診斷,NAFLD的髮生率為36.62%(52/142);PCOS 患者中已婚患者的NAFLD髮病率(37.50%)與未婚患者的NAFLD髮病率(33.33%)之間差異無統計學意義(P>0.05);肥胖PCOS 患者中NAFLD的髮病率(66.07%)明顯高于非肥胖NAFLD的髮病率(17.44%),且差異有統計學意義(P<0.05);NAFLD組上述各項生化、代謝指標均大于非NAFLD組,且差異均有統計學意義(P<0.05).結論:控製體重、適量運動、低脂飲食、改善胰島素牴抗、早期檢測和榦預是防止PCOS 患者中NAFLD髮生的重要措施.
목적:조사다낭란소종합정(PCOS)중비주정성지방간(NAFLD)적발병정황병대상관위험인소주출분석.방법:장본원2001년2월~2010년3월수치적142례PCOS환자안조B초진단분위량조,비NAFLD조92례,NAFLD조50례,비교량조지간BMI、To、FINS、2hINS、Homa-IR、CHO、ALT、AST등생화、대사지표.결과:142례PCOS 환자경B초진단,NAFLD적발생솔위36.62%(52/142);PCOS 환자중이혼환자적NAFLD발병솔(37.50%)여미혼환자적NAFLD발병솔(33.33%)지간차이무통계학의의(P>0.05);비반PCOS 환자중NAFLD적발병솔(66.07%)명현고우비비반NAFLD적발병솔(17.44%),차차이유통계학의의(P<0.05);NAFLD조상술각항생화、대사지표균대우비NAFLD조,차차이균유통계학의의(P<0.05).결론:공제체중、괄량운동、저지음식、개선이도소저항、조기검측화간예시방지PCOS 환자중NAFLD발생적중요조시.
Objective:To investigate the incidence of non-alcoholic fatty liver disease (NAFLD) with polycystic ovary syndrome (PCOS) and to analyze the related risk factors.Methods:142 PCOS patients were divided into two groups according to the B ultrasonic diagnosis, 92 cases in non-NAFLD group and 50 cases in NAFLD group.Compare the indicators such as BMI, To, FINS, 2hINS, Homa-IR, CHO, ALT and AST.Results:In 142 patients with PCOS, the incidence rate of NAFLD was 36.62% (52 /142); there were no statistical differences between the incidence of married patients with NAFLD (37.50%) and unmarried patients with NAFLD (33.33%) (P>0.05); the incidence of NAFLD in obese PCOS patients (66.07%) was significantly higher than the incidence of NAFLD in non-obese (17.44%), and the difference was statistically significant (P<0.05); of NAFLD group the various biochemical, metabolic indicators were greater than the non-NAFLD group, and the differences were statistically significant (P<0.05).Conclusion:weight control, regular exercise, low-fat diet, improving insulin resistance, early detection and intervention are important measures to prevent NAFLD occurring in patients with PCOS.
