CAJ | 학술논문

目的:探讨原发性高血压(PH)颈脑动脉狭窄的患病情况及其与血管疾病危险因素的关系.方法:对217例Ⅱ级PH患者进行头颈部联合CT血管造影(CTA)、身高、体重、总胆固醇(TC)、甘油三酯(TG)、空腹血糖(FBS)和血尿酸(SUA)检测,对结果进行探索性分析.结果:颈动脉狭窄19例(患病率8.8%),脑动脉狭窄107例(患病率49.3%),脑动脉闭塞9例(患病率4.1%),颈动脉和脑动脉均有狭窄17例(患病率8.3%),动脉狭窄或闭塞组其体质指数(BMI)、TC、TG、FBS和SUA的平均值较非动脉硬化组高(P<0.01).高血压和SUA、TC、BMI、和FBS与脑血管的狭窄有协同作用.结论: PH颈脑动脉狭窄患病率较高,脑动脉狭窄或闭塞患病率远高于颈动脉狭窄患病率,动脉狭窄或闭塞的PH患者,其BMI、TC、TG、FBS和SUA的平均值较动脉正常组高,SUA、TC和FBS是高血压动脉狭窄的重要危险因素,高血压和SUA、TC、BMI、和FBS与动脉狭窄有协同作用.
목적:탐토원발성고혈압(PH)경뇌동맥협착적환병정황급기여혈관질병위험인소적관계.방법:대217례Ⅱ급PH환자진행두경부연합CT혈관조영(CTA)、신고、체중、총담고순(TC)、감유삼지(TG)、공복혈당(FBS)화혈뇨산(SUA)검측,대결과진행탐색성분석.결과:경동맥협착19례(환병솔8.8%),뇌동맥협착107례(환병솔49.3%),뇌동맥폐새9례(환병솔4.1%),경동맥화뇌동맥균유협착17례(환병솔8.3%),동맥협착혹폐새조기체질지수(BMI)、TC、TG、FBS화SUA적평균치교비동맥경화조고(P<0.01).고혈압화SUA、TC、BMI、화FBS여뇌혈관적협착유협동작용.결론: PH경뇌동맥협착환병솔교고,뇌동맥협착혹폐새환병솔원고우경동맥협착환병솔,동맥협착혹폐새적PH환자,기BMI、TC、TG、FBS화SUA적평균치교동맥정상조고,SUA、TC화FBS시고혈압동맥협착적중요위험인소,고혈압화SUA、TC、BMI、화FBS여동맥협착유협동작용.
Objective:To study the relationship between the risk factor of vascular disease and patients with carotid and cerebral arteries stenosis and primary hypertension(PH).Methods:217 cases with PH Ⅱ were chosen.they were given CT angiography of carotid and cerebral arteries(CTA) and examined the height,weight,TC,TG,FBS,and SUA.The results were analyzed.Results:19 cases with carotid arteries stenosis(the morbidity was 8.8%),107 cases with cerebral arteries stenosis(morbidity was 49.3%),9 cases with Cerebral artery occlusion(morbidity was 4.1%),17 cases with carotid and cerebral arteries stenosis s(morbidity was 8.3%),the mean of BMI,TC,TG,FBS and SUA in arteries stenosis or occlusion patients were higher than those of arteriosclerosis patients.There was cooperative effect between hypertension,SUA,TC,BMI,FBS and cerebral arteries stenosis.Conclusion:The morbidity of carotid and cerebral arteries stenosis with PH is high,the morbidity of cerebral arteries stenosis or occlusion is higher than that of carotid arteries stenosis,the mean of BMI,TC,TG,FBS and SUA in arteries stenosis or occlusion patients with PH is higher than the normal group.SUA、TC and FBS are the risk factor of carotid and cerebral arteries stenosis with PH.There is cooperative effect between hypertension,SUA,TC,BMI,FBS and cerebral arteries stenosis.