CAJ | 학술논문

目的:评价我院三种治疗2型糖尿病方法的临床疗效及经济成本.方法:选择我院273例2型糖尿病患者,随机分为三组,实施三种联合用药治疗方案.A组二甲双胍+格列本脲,B组二甲双胍+阿卡波糖,C组阿卡波糖+瑞格列奈;定期对各组患者的血糖水平进行监测,经过6个月的治疗,进行经济效果、不良反应及药物疗效分析.结果:三组在治疗后的FPG、PGB、HbA1c均得到较理想的控制.A、B、C组总有效率分别为82.4%,84.6%和85.7%(P>0.05)无显著性差异;A、B、C、组成本-效果比(C/E)分别为1.376、16.276和23.733,B、C组对于A组的增量成本-效果比(△C/△E)分别为74.36和582.0.结论:各组治疗2型糖尿病的用药方案疗效均较好,但从经济成本及总有效率等方面综合考虑,二甲双胍+格列本脲方案为较佳选择.
목적:평개아원삼충치료2형당뇨병방법적림상료효급경제성본.방법:선택아원273례2형당뇨병환자,수궤분위삼조,실시삼충연합용약치료방안.A조이갑쌍고+격렬본뇨,B조이갑쌍고+아잡파당,C조아잡파당+서격렬내;정기대각조환자적혈당수평진행감측,경과6개월적치료,진행경제효과、불량반응급약물료효분석.결과:삼조재치료후적FPG、PGB、HbA1c균득도교이상적공제.A、B、C조총유효솔분별위82.4%,84.6%화85.7%(P>0.05)무현저성차이;A、B、C、조성본-효과비(C/E)분별위1.376、16.276화23.733,B、C조대우A조적증량성본-효과비(△C/△E)분별위74.36화582.0.결론:각조치료2형당뇨병적용약방안료효균교호,단종경제성본급총유효솔등방면종합고필,이갑쌍고+격렬본뇨방안위교가선택.
Objective:To evaluate the clinical and economic effects of three hypoglycemic drugs for type 2 diabetes. Methods:273 cases of type 2 diabetes were randomly divided into 3 groups,each group 91 persons.Group A was treated by Metformin combined with Glibenclamide;Group B was treated by Metformin combined with Acarbose; Group C was treated by Acarbose combined with Repaglinide. The blood glucose level of patients in each group was regularly monitored.The economic effectiveness,adverse reactions,and medication effects were analyzed before treatment and after 6 months treatment.Results:The FPG, PBG and HbA1c of three groups were ideally controlled.The total effective rates of group A, B and C were 82.4%,84.6% and 85.7%, respectively (P>0. 05).The cost-effect ratio of group A、B、C is respectively:1.376、16.276 and 23.733.The overrun cost-effect ratio of group B、C to group A is 574.36 and 582.0, respectively.Conclusion:The three groups of treatment of type 2 diabetes have better efficacy of the program.However,considering from cost and total effective rate,the scheme Metformin combined with Glibenclamide is the better choice.