中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2012年
36期
264-265
,共2页
中期妊娠%唐氏综合征%产前筛查
中期妊娠%唐氏綜閤徵%產前篩查
중기임신%당씨종합정%산전사사
Middle period pregnancy%Down's syndrome%Prenatal screening
目的分析2702例孕妇中期胎儿唐氏征筛查结果,探讨孕妇中期胎儿唐氏征产前筛查的临床意义.方法采用贝克曼库尔特全自动化学发光酶免分析仪及原装试剂,对孕14~20+6周的孕妇血清进行甲胎蛋白(AFP)、人绒毛膜促性激素β亚基(β-HCG)及游离雌三醇(uE3)检测,并将孕妇的相关信息和检测的 AFP、β-HCG、uE3结果输入“腾程筛查软件”中,进行三联检测的结果运算,得出一个概率指标.结果唐氏综合征(DS)筛查结果高危例数有65例,总阳性率为2.41%;其中:20~24岁年龄组的孕妇唐氏综合征筛查结果高危例数有11例(1.76%)25-29岁年龄组的孕妇唐氏综合征筛查结果高危例数有26例(1.93%);30-35岁年龄组的孕妇唐氏综合征筛查结果高危例数有9例(2.77%);>35岁年龄组的孕妇唐氏综合征筛查结果高危例数有19例(4.73%).结论在中期孕妇进行唐氏综合征三联筛查是必要的,能够提高唐氏患儿的早期发现和诊断,是降低唐氏患儿出生率的有效方法.
目的分析2702例孕婦中期胎兒唐氏徵篩查結果,探討孕婦中期胎兒唐氏徵產前篩查的臨床意義.方法採用貝剋曼庫爾特全自動化學髮光酶免分析儀及原裝試劑,對孕14~20+6週的孕婦血清進行甲胎蛋白(AFP)、人絨毛膜促性激素β亞基(β-HCG)及遊離雌三醇(uE3)檢測,併將孕婦的相關信息和檢測的 AFP、β-HCG、uE3結果輸入“騰程篩查軟件”中,進行三聯檢測的結果運算,得齣一箇概率指標.結果唐氏綜閤徵(DS)篩查結果高危例數有65例,總暘性率為2.41%;其中:20~24歲年齡組的孕婦唐氏綜閤徵篩查結果高危例數有11例(1.76%)25-29歲年齡組的孕婦唐氏綜閤徵篩查結果高危例數有26例(1.93%);30-35歲年齡組的孕婦唐氏綜閤徵篩查結果高危例數有9例(2.77%);>35歲年齡組的孕婦唐氏綜閤徵篩查結果高危例數有19例(4.73%).結論在中期孕婦進行唐氏綜閤徵三聯篩查是必要的,能夠提高唐氏患兒的早期髮現和診斷,是降低唐氏患兒齣生率的有效方法.
목적분석2702례잉부중기태인당씨정사사결과,탐토잉부중기태인당씨정산전사사적림상의의.방법채용패극만고이특전자동화학발광매면분석의급원장시제,대잉14~20+6주적잉부혈청진행갑태단백(AFP)、인융모막촉성격소β아기(β-HCG)급유리자삼순(uE3)검측,병장잉부적상관신식화검측적 AFP、β-HCG、uE3결과수입“등정사사연건”중,진행삼련검측적결과운산,득출일개개솔지표.결과당씨종합정(DS)사사결과고위례수유65례,총양성솔위2.41%;기중:20~24세년령조적잉부당씨종합정사사결과고위례수유11례(1.76%)25-29세년령조적잉부당씨종합정사사결과고위례수유26례(1.93%);30-35세년령조적잉부당씨종합정사사결과고위례수유9례(2.77%);>35세년령조적잉부당씨종합정사사결과고위례수유19례(4.73%).결론재중기잉부진행당씨종합정삼련사사시필요적,능구제고당씨환인적조기발현화진단,시강저당씨환인출생솔적유효방법.
Objective To discussed the middle for pregnant women fetal down the clinical significance of prenatal screening,2702 cases were analyzed for pregnant women fetus down the middle screening results. Methods Used the Beckman Kurt automatic chemiluminescence enzyme from analyzer and original reagent to detection of AFP, β-HCG and uE3 content in pregnant women of 14~20+6 weeks. Pregnant women's information and AFP, β-HCG and uE3 assessment input "Tengcheng software" for joint screening, get a probability index. Results Down syndrome (DS) screening high-risk number results 65 cases, the total prevalence rate was 2.41%; Among them: 20~24 years old age group of pregnant women down's syndrome screening results have high-risk number 11 cases(1.76%); 25~29 age group of pregnant women down's syndrome screening results high-risk number 26 cases (1.93%); 30~35 years old age group of pregnant women down's syndrome screening high-risk number results 9 cases(2.77%); >35years old age group of pregnant women down's syndrome screening high-risk number results in 19 cases (1.73%). Conclusion In the middle of pregnant women to press down's syndrome screening is necessary, to improve the children and early detection of Down's syndrome diagnosis, is to reduce the effective method to children with down's birth rate.
