CAJ | 학술논문

目的考察钙通道阻滞剂对高血压的临床治疗效果.方法将220例高血压患者随机分为观察组和对照组各110例,观察组采用非洛地平缓释片进行治疗,对照组采用硝苯地平片进行治疗.结果两组治疗后的 SBP 和 DBP 均优于较治疗前有显著改善(P<0.05),且观察组 SBP 和 DBP 下降程度明显低于对照组(P<0.05);总有效率观察组为91.82%,对照组为78.18%,比较具统计学意义(P<0.05);不良反应发生率观察组为5.5%,对照组为13.64%,观察组显著优于对照组(P<0.05).结论非洛地平缓释片治疗高血压疗效理想,安全可靠,值得在临床中推广应用.
목적고찰개통도조체제대고혈압적림상치료효과.방법장220례고혈압환자수궤분위관찰조화대조조각110례,관찰조채용비락지평완석편진행치료,대조조채용초분지평편진행치료.결과량조치료후적 SBP 화 DBP 균우우교치료전유현저개선(P<0.05),차관찰조 SBP 화 DBP 하강정도명현저우대조조(P<0.05);총유효솔관찰조위91.82%,대조조위78.18%,비교구통계학의의(P<0.05);불량반응발생솔관찰조위5.5%,대조조위13.64%,관찰조현저우우대조조(P<0.05).결론비락지평완석편치료고혈압료효이상,안전가고,치득재림상중추엄응용.
Objective? Investigation the calcium channel blocker to hypertension clinical therapeutic effect. Methods 220 cases of hypertension patients were randomly divided into observation group and control group each 110 examples, the observation group using felodipine 53:25 treatment, control group using nifedipine tablet treatment. Results The two groups after treatment of SBP and DBP is better than a before treatment improed significantly (P<0.05), and the observation group SBP and DBP decline significantly lower than that in control group (P<0.05); The total effective rate observation group is 91.82%, to 78.18% in the placebo group, compared with statistical significance (P<0.05); Adverse reaction rate observation group is 5.5%, to 13.64% in the placebo group, the observation group is significantly better than that in control group (P<0.05). Conclusion Felodipine 53:25 curative effect in the treatment of hypertensive ideal, safe and reliable, it is worth in the clinical application.