CAJ | 학술논문

目的探讨米力农和多巴胺对肺炎合并心力衰竭(CHF)患儿的临床疗效.方法将89例患儿随机分为三组,A组为常规组,B组为米力农组[0.75μg/(kg·min)],C组为多巴胺组[5μg/(kg·min)],米力农和多巴胺采用微量泵泵入,3d后观察对比三组患儿的心率(HR)、血压(BP)、肺动脉压力(PAP)、中心静脉压(CVP)、B型尿钠肽(BNP)、左室射血分数(LVEF)、左室收缩时间间期(LVSTI)、右室射血分数(RVEF)、右室收缩时间间期(RVSTI)、副反应发生率.结果三组HR无统计学差异;组A的BP、LVEF明显低于组B和组C,组B的PAP、CVP和RVSTI明显低于组A和组C,组A的BNP明显高于组B和组C,组B的RVEF明显高于组C,组C的RVEF明显高于组A;结论米力农和多巴胺均能改善肺炎合并心力衰竭患儿的心功能,米力农对右心功能的改善较多巴胺更为明显.
목적탐토미력농화다파알대폐염합병심력쇠갈(CHF)환인적림상료효.방법장89례환인수궤분위삼조,A조위상규조,B조위미력농조[0.75μg/(kg·min)],C조위다파알조[5μg/(kg·min)],미력농화다파알채용미량빙빙입,3d후관찰대비삼조환인적심솔(HR)、혈압(BP)、폐동맥압력(PAP)、중심정맥압(CVP)、B형뇨납태(BNP)、좌실사혈분수(LVEF)、좌실수축시간간기(LVSTI)、우실사혈분수(RVEF)、우실수축시간간기(RVSTI)、부반응발생솔.결과삼조HR무통계학차이;조A적BP、LVEF명현저우조B화조C,조B적PAP、CVP화RVSTI명현저우조A화조C,조A적BNP명현고우조B화조C,조B적RVEF명현고우조C,조C적RVEF명현고우조A;결론미력농화다파알균능개선폐염합병심력쇠갈환인적심공능,미력농대우심공능적개선교다파알경위명현.
Objective To observe clinical effect of milrinone and dopamine on children suffering from pneumonia complicated with heart failure. Methods 89 patients were randomly divided into group A, group B(milrinone) and group C( dopamine).To observe the index varieties about heart rate(HR), blood pressure(BP), pulmonary artery pressure(PAP), central venous pressure(CVP), brain natriuretic peptide(BNP), left ventricular ejection fraction(LVEF), left ventricular systolic time interval( LVSTI), right ventricular ejection fraction (RVEF), right ventricular systolic time interval(RVSTI), and side effect rate. Results HR of three groups had no statistical difference.BP and LVEF of group A were statisticaly lower than group B and group C. PAP,CVP and RVSTI of group B were statisticaly lower than group A and group C.BNP of group A was statisticaly higher than group B and group C. RVEF of group B was statisticaly higher than group C. RVEF of group C was statisticaly higher than group A. Conclusion Milrinone and dopamine have both obvious improvement on cardiac functions of children suffering from pneumonia complicated with heart failure, and milrinone is more effective than dopamine in improving the function of right heart.