CAJ | 학술논문

目的探讨我院抗精神病药物所致不良反应(ADR)的发生情况,为合理用药提供参考.方法收集我院2010年-2011年的471例抗精神病药物所发生的ADR报告,对患者性别、年龄、合并用药及不良反应临床表现等情况进行统计、分析.结果本院上报的抗精神病药物发生的不良反应主要发生在21~60岁;累及10个系统-器官,主要以神经系统不良反应(28.03%)及心血管系统不良反应(19.32%)最常见.结论医疗机构应重视抗精神病药引起的不良反应,加强抗精神病药的合理应用.
목적탐토아원항정신병약물소치불량반응(ADR)적발생정황,위합리용약제공삼고.방법수집아원2010년-2011년적471례항정신병약물소발생적ADR보고,대환자성별、년령、합병용약급불량반응림상표현등정황진행통계、분석.결과본원상보적항정신병약물발생적불량반응주요발생재21~60세;루급10개계통-기관,주요이신경계통불량반응(28.03%)급심혈관계통불량반응(19.32%)최상견.결론의료궤구응중시항정신병약인기적불량반응,가강항정신병약적합리응용.
Objective To investigate the antipsychotic induced adverse drug reaction (ADR) occurred in our hospital, and provide advice for the rational use of drugs. Methods To conduct a statistical analysis based upon the information from 471 inpatients with ADR which were reported from 2010-2011 in my hospital such as gender, age, drug combination etc. Results ADR is likely to be reported in various ages section during inpatients, particularly those are 20-60 years old. It involves ten systems, will mainly cause the central nervous system damage (28.03%) and cardiovascular system (19.32%). Conclusion Medical institutions should pay attention to antipsychotic induced adverse and rational use of it.